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  • by Nicola Boulton September 01, 2022 5 min read

    CBD for Back Pain: Your Complete Guide

    Cannabidiol (CBD), a non-psychoactive cannabis compound, promotes health and well-being. This molecule interacts with the endocannabinoid system, helping consumers with back pain problems. This guide investigates their relationship.

    Cannabidiol (CBD), a nutrient-rich cannabinoid compound, comes from the cannabis family. Cannabis is categorized into hemp and cannabis sativa (marijuana) species. The former contains a high cannabidiol profile, unlike the latter. Therefore, most manufacturers derive CBD, a non-psychoactive compound, from hemp plants. It has neuroprotective, antipsychotic, antiemetic, anti-oxidative, and anti-inflammatory properties. Back pain is prevalent among people of different races and ages, although it affects seniors mostly. Commercial drugs are expensive and come with certain negative side effects. Most patients prefer natural supplements for back problems. CBD's properties and its interaction with the endocannabinoid system addresses pain disorders. This guide investigates the relationship between CBD and back pain.

    Cannabidiol and Back pain

    According to Webb & Webb (2014), most consumers use cannabidiol to help and soothe different health disorders such as anxiety, chronic pain, nausea, insomnia, and depression. While the scientific study is inadequate, back pain patients report positive outcomes for using cannabidiol. Traditionally, individuals use various drugs to fight back pain. They include:

    • Natural response modifiers aim at diverse proteins responsible for the immune system.
    • Corticosteroids de-escalate inflammation and subdue the human immune system.
    • Painkillers to decrease pain
    • Disease-modifying antirheumatic drugs (DMARDs) that restrain the immune system.
    • Counterirritants disrupt pain signal transmission.

    Although these drugs are beneficial, their prolonged safety is ambiguous. Consumers who utilize them frequently might develop stomach, liver, kidney, and heart problems. Overdosing these medications or consuming them for a lengthy period may trigger liver disorders in certain instances. Most patients have discovered alternative management techniques such as physical therapy or routine adjustments. Nowadays, cannabidiol is a renowned natural alternative with minimal undesirable side effects. Malek & Starowicz (2016) showed that cannabidiol interrelates with the body's endocannabinoid system (ECS) to decrease pain and inflammation. The study above also suggested that this complex cell-signaling system controls various body processes, including pain output, appetite, energy levels, fertilization, sleep, metabolism, mood, immune system, and homeostasis (a body state equilibrium). Cannabidiol interacts with endocannabinoid receptors in the human nervous system and brain, leading to the absorption of hormones and particular compounds. It affects how the human brain detects pain and elevates serotonin levels by interrelating with serotonin neurotransmitters. This generates relaxation in your brain, lowering the back pain intensity. Also, cannabinoids inhibit particular receptors that interfere with pain and inflammation in your body. cannabidiol impedes neurotransmitters that permit endocannabinoids and anandamide to escalate in your body. This influences how receptors react to impulses received, which lowers pain and inflammation.

    What is CBD?

    Cannabidiol, an essential cannabinoid compound, comes from the cannabis family. Cannabis is grouped into cannabis sativa (marijuana) and hemp plants. The former contains high tetrahydrocannabinol (THC) contents but low cannabidiol. Contrastingly, hemp constitutes a high cannabidiol profile but insignificant THC molecules. THC is an active cannabis compound responsible for psychoactive and euphoric effects in marijuana products. Most brands manufacture cannabidiol, a non-psychoactive compound from hemp plants. Federal laws directed that hemp-derived cannabidiol products contain 0.3 percent or below THC legal level. Otherwise, those with greater amounts are schedule 1 substances, the prohibited marijuana-related products. Certain US States authorize marijuana products for medicinal and recreational purposes only.

    Cannabidiol is categorized into isolates, broad-spectrum, and whole-plant spectrum. Isolates are the purest cannabidiol extracts as they contain cannabidiol contents purely. Unfortunately, these extracts have the least nutritional profile among their counterparts since beneficial ingredients are isolated from the final product. Broad-spectrum products constitute whole plant constituents except THC content. This non-THC extract generates an entourage effect but is lower than full-spectrum. The extract appropriates enthusiasts to enjoy whole plant benefits without experiencing psychoactive and euphoric effects from the THC compound. Whole-plant products contain full plant constituents, including cannabigerol, terpenes, cannabichromene, flavonoids, fatty acids, THC, cannabinol, and essential oils. The components work synergistically to generate the entourage effect. This phenomenon occurs when each element's benefits are amplified to produce more potent results. Whole-plant products contain a grassy and nutty taste because fragrant molecules like terpenes are present. The THC substance in the extract is insufficient to intoxicate consumers but can make them fail drug screening tests. They suit consumers who tolerate THC effects and all compounds in cannabis plants. Consumers should purchase cannabidiol products from reputable manufacturers who extract them from hemp through carbon dioxide. This technique is standard since no harmful solvent deposits remain on the end product. Also, this helps customers purchase safe and effective products that impact back pain significantly.

    Inflammation and Cannabidiol

    Lin et al. (2018) stated that cannabidiol subdues inflammatory responses, reducing back pain. Periphery and brain contain CB2 receptors in minimal amounts but exist in high concentrations in immune tissues. Cannabinoids that attach CB2 neurotransmitters might contain anti-inflammatory impacts that manufacture de-escalate cell messengers (cytokine). According to Yang et al. (2012), cannabidiol attaching to CB2 receptors reduces response when the human immune system detects a problem, especially when the body has pain. Prolonged pain or inflammation escalates oxidative stress risks, directly interfering with your tissues and healthy organs. Back pain might result from illness or injury and may last longer if untreated. Its severity differs among patients and might deteriorate their health, thus lowering life quality.

    Cannabidiol Boosts Sleep

    Quality sleep promotes health and wellness, but most people hardly have it. Those suffering from back pain, especially chronic disorders, have sleeping inconsistencies. This might deteriorate their health condition and could be fatal in certain instances. Zhao (2019) proved that cannabidiol induces sleepiness in consumers by preventing adenosine re-absorption, thus enabling them to enjoy a good restful night's sleep. Also, the anti-inflammatory properties fight pains and inflammations, making you sleep better.


    Back pain affects people from different races, especially seniors. It disrupts normal body functioning by interrupting general health and wellness. Some curative measures employed by traditional people include painkillers, corticosteroids to alleviate inflammation, and counterirritants to disrupt pain signal transmission. Although these measures are beneficial, their long-term effects are ambiguous. Currently, cannabidiol, a natural and non-psychoactive supplement, contains infinite potential benefits. Cannabidiol affects how the patient's brain detects pain and elevates serotonin levels by interrelating with serotonin neurotransmitters. This generates relaxation in your brain, lowering the back pain. However, invest in high-quality cannabidiol products to achieve the best results.


    Lin, X., Dhopeshwarkar, A. S., Huibregtse, M., Mackie, K., & Hohmann, A. G. (2018). Slowly Signaling G Protein–Biased CB2 Cannabinoid Receptor Agonist LY2828360 Suppresses Neuropathic Pain With Sustained Efficacy And Attenuates Morphine Tolerance And Dependence. Molecular Pharmacology, 93(2), 49-62.

    Malek & Starowicz (2016). Dual-Acting Compounds Targeting Endocannabinoid And Endovanilloid Systems—A Novel Treatment Option For Chronic Pain Management. Frontiers In Pharmacology, 7, 257.

    Webb, & Webb (2014). Therapeutic Benefits Of Cannabis: A Patient Survey. Hawai'i Journal Of Medicine & Public Health, 73(4), 109.

    Yang, P., Wang, L., & Xie, X. Q. (2012). Latest Advan: novel Cannabinoid CB2 Ligands For Drug Abuse And Their Therapeutic Potential. Future Medicinal Chemistry, 4(2), 187-204.

    Zhao, Z. (2019). Role Of The Type-1 Cannabinoid Receptor In The Control Of Water Intake (Doctoral Dissertation, Université De Bordeaux).

    Nicola Boulton
    Nicola Boulton

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