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  • by Nicola Boulton September 15, 2022 5 min read

    Can CBG Help with Constipation?

    Cannabigerol (CBG), a cannabis derivative, is praised for its infinite therapeutic benefits. Constipation is a therapeutic disorder wherein an individual battles to release stool from the system regardless of the extended attempting period. CBG has calming, anti-inflammatory, and analgesic properties that address this problem.

    Previously, scientists focused on major cannabis compounds like tetrahydrocannabinol (THC) and cannabidiol (CBD) while despising the minor ones. Besides CBG being a minor cannabis compound, it functions as a precursor of other cannabis compounds. It naturally breaks down into various plant compounds, meaning old cannabis plants have insignificant CBG amounts. Unlike THC, CBD and CBG do not have psychoactive and euphoric effects. Cannabigerol consists of analgesic, anti-inflammatory, and antifungal properties, making it suitable for maintaining good health and wellness. For this reason, this blog will investigate whether CBG addresses constipation.

    What is Constipation?

    According to Thompson et al. (2021), constipation is a therapeutic disorder wherein an individual battles to release stool from the system regardless of the extended attempting period. The fundamental trigger is irregular bowel movements that could escalate abdominal pain. This pain continually increases since food waste accumulates within your bowels without making notable movements. Currently, this agonizing therapeutic issue has numerous triggers. Nevertheless, professional doctors and healthcare specialists categorize the following ass major constipation causes:

    • Lack of activity or physical exercise
    • Long-term stress
    • Side effects related to different medications.
    • Insufficient fiber in your food (not consuming enough amount of grain foods, fruits, and vegetables)
    • Inadequate hydration
    • Chronic anxiety and depression
    • Poor eating routine
    • Insufficient essential vitamins

    Medical providers report that individuals with constipation become shy and never share their problems with others. Thus, most folks handle constipation as an unusual health disorder. Essentially, constipation is not an ailment but signifies other present diseases.

    The CBG Effects on Constipation

    Most users wonder whether cannabigerol is beneficial to those battling constipation. Like CBD, CBG has anti-inflammatory and calming properties which relax your whole body regardless of using it in edible or oil form. Cannabigerol products can come in topical ointments, tinctures, or capsules. Any product formulation ensures CBG enters your body to deliver anticipated benefits without adverse side effects. Therefore, it carries the potential to address constipation problems. Individuals can eliminate pain resulting from irregular and infrequent bowel movements via cannabigerol. The flight or fight reaction of the activated nervous system decreases to permit relaxation. The cannabigerol attaches to body receptors which reduces pain.

    How Cannabigerol Functions

    Cannabigerol is a nutrient-rich product within the cannabis domain since its interaction and composition with the human endocannabinoid system remains exceptional. Cannabidiol interacts with peripheral (allosteric) location on a CB2 neurotransmitter. Contrastingly, cannabigerol bind the active (orthosteric) position of CB2. According to Jakowiecki et al. (2021), the orthosteric position is the major receptor location, while the allosteric site supports modulation. Cannabigerol directly binds to the body's active neurotransmitter site, while various cannabinoids cannot. This triggers more effective and quicker inflammation relief. Cannabigerol functions like a GABA re-absorption neurotransmitter resulting in higher GABA brain levels. The GABA receptor causes considerable impacts on muscle relaxation, pain, anxiety, and sleep. Cannabigerol might relieve muscle relaxation and pain better than cannabidiol or THC.

    Can CBG Address Irritable Bowel Syndrome (IBS)?

    Irritable bowel syndrome results from intestinal problems, although its leading cause is unknown. IBS triggers symptoms, including belly cramping, bloating, gas, and pain. It has two main varieties including:

    • Irritable bowel syndrome with diarrhea. This problem stimulates belly pain or cramps, an urgency to move the bowels, and loose stool.
    • Irritable bowel syndrome with constipation. It prompts constipation symptoms besides a desire to move without the capability.

    Though experts have no sufficient evidence regarding the IBS causes, the condition is treatable. According to Alharthi et al. (2013), irritable bowel syndrome affects approximately thirty-five million United States residents. The disorder is sometimes painful and uncomfortable but cannot cause cancer. Although experts report that IBS cannot result from diet or stress, these triggers can worsen its state. For this reason, they encourage individuals to maintain a personal diary that assists in discovering causes that deteriorate the symptoms. Researchers claim that women are more vulnerable to IBS than men. Most folks with this problem have below fifty years through those beyond here are susceptible to IBS. The symptoms vary from slight problems to extreme debilitation, which is irregular. This depicts that this problem might prompt social isolation. The following are some factors that participate in symptoms development, including:

    Severe Infection

    Certain individuals get irritable bowel syndrome after an extreme gut contagion from viruses or bacteria.

    Early Life Stress

    Individuals with childhood stressful or traumatic events experience greater IBS susceptibility.

    Muscle Intestinal Contractions

    Shrinkages that force food via the human digestive system persists longer than usual. This could trigger diarrhea, bloating, and gas. In this regard, weak contractions decelerate food passage resulting in constipation.

    Nervous System

    Inappropriate coordination between brain, gut, and nerve signals distorts the digestive system.

    Gut Microbiome Fluctuations

    The human gut contains an excellent harmful and beneficial bacteria balance. Researchers reveal that individuals with IBS contain a unique microbiome than strong ones.

    CBG Benefits

    According to Gruber et al. (2016), cannabigerol provides exceptional therapeutic benefits in gut health, intriguingly and anxiety, neuro-inflammation, blood pressure, sleep, and pain management. Recently, experts have referred to the human gut as another brain that promotes gut health, overall health, cognitive function, and mood. Furthermore, it exerts curative and preventative impacts in certain colitis forms and promotes ROS production, which shields your intestines against inflammation.

    Several consumers have reported significant recovery in health conditions such as joint pain, muscle, sleep, blood pressure, constipation, abdominal distinction, and bloating. Cannabigerol functions as a beneficial CB2 activator and CB1 inhibitor, causing such biochemical reactions. Alpha-2 adrenergic neurotransmitter agonist treatments participate in treating addiction, neurosis, depression, and anxiety. However, consider high-quality CBG products to reap optimum benefits.


    Cannabigerol (CBG), a cannabis derivative, is praised for its infinite therapeutic benefits. It has anti-inflammatory, antifungal, analgesic, and calming properties which relaxes the human body. CBG comes in topicals, tinctures, oils, gummies, and capsules. Individuals can choose any suitable formulation to enjoy cannabigerol benefits. Different consumption methods have unique onset periods, and the effects remain for varying times. Constipation is a therapeutic disorder wherein an individual battles to release stool from the system regardless of the extended attempting period. Cannabidiol interacts with peripheral (allosteric) location on a CB2 neurotransmitter, while cannabigerol binds the active (orthosteric) position of CB2. Consequently, positive effects on constipation are experienced.


    Alharthi, Alhakami, & Alhejaili (2013). Irritable Bowel Syndrome: Prevalence, Type and Associated Factors among Male Adult residents at Al-Iskan Avenue in Makkah Almukarramah, Saudi Arabia. American Journal of Research Communication, 1(11), 98-122.

    Gruber, Sagar, Dahlgren, Racine, Smith, & Lukas (2016). Splendor in the grass? A pilot study assessing the impact of medical marijuana on executive function. Frontiers in Pharmacology, 355.

    Jakowiecki, Abel, Orzeł, Pasznik, Preissner, & Filipek (2021). Allosteric Modulation of the CB1 Cannabinoid Receptor by Cannabidiol—A Molecular Modeling Study of the N-Terminal Domain and the Allosteric-Orthosteric Coupling. Molecules, 26(9), 2456.

    Thompson, A. P., MacDonald, S. E., Wine, E., & Scott, S. D. (2021). Understanding parents' experiences when caring for a child with functional constipation: interpretive description study. JMIR pediatrics and parenting, 4(1), e24851.

    Nicola Boulton
    Nicola Boulton

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