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  • by Nicola Boulton September 15, 2022 5 min read

    Can CBG Help with Depression?

    Depression is one of the most common mental issues affecting many people. Thankfully, recent research suggests that cannabinoids could be the go-to solution. This article will explain more about CBG and whether it can alleviate depression.

    If you are an avid cannabis user, you may be well acquainted with CBD. However, its sister cannabinoid, CBG, could also be great for relieving depression. Although there isn't sufficient evidence of its efficacy, more people are embracing it because it is an organic compound with minimal side effects. Furthermore, it has no psychoactive effects and cannot cause a 'high' or intoxicating sensation when consumed. CBG can be consumed in various forms, such as gummies, capsules, and tinctures. Read on to determine whether CBG can help with depression. Furthermore, you will discover the numerous ways through which you can take CBG for depression.

    CBG for Depression

    It is important to note that research studies on the efficacy of CBG for depression are limited. However, there are reports of patients with depression who have massively benefited from using CBG. Therefore, this cannabinoid is a new area of increasing interest in researching alternative wellness products.

    Interestingly, the other cannabinoids originate from CBGA, an acidic form of CBG. The beauty of using CBG is that it does not contain intoxicating effects. Therefore, you can comfortably use it without the fear of getting "high."

    From anecdotal evidence and research, CBG impacts the production and retention of the brain's neurotransmitters. The same is true with CBD and other cannabinoids.

    Also, CBG affects the production of dopamine in your system. According to Dawson et al. (2021), CBG can maintain the levels of anandamide in your brain by providing relaxation. Anandamide is a neurotransmitter that affects your overall well-being and regulates sleep, mood, and anxiety levels. Unfortunately, when enzymes in the body break it down, the implications are evident in your moods. Thankfully, CBG helps prevent its breakdown.

    Moreover, anandamide is important because it aids in increasing dopamine levels. When dopamine levels are significantly low, you tend to experience depression, lack motivation, and have different mood disorders that impact your productivity.

    Therefore, CBG can help with depression. According to Martinelli et al. (2021), it preserves the anandamide in your body, influencing dopamine production levels. So, you can consider taking CBG to increase dopamine and, in the end, elevate your mood and address depression or even reduce its occurrences.

    Notably, you may choose to combine CBD and CBG to get entourage effects for your depression. This way, you don't isolate a cannabinoid and focus on its potential benefits alone. Rather, you can obtain the best benefits from both worlds, thus addressing your depression more effectively. Learn more about cbd for gut health

    CBD for Depression; What Do Research Say?

    At this point, you may wonder what the limited research on CBG mentions on its use for depression. Some researchers have analyzed the effects of using CBG in individuals with anxiety and depression after a while. According to Burstein (2015), using CBG helped reduce depression by targeting its root cause, such as inflammation. Therefore, a majority indicated that their condition improved.

    Besides, others mentioned that using CBG-rich products positively impacted their behavior and alleviated their depression. Interestingly, 80% of the respondents mentioned that CBG was a better alternative for addressing depression than other traditional or inorganic treatment methods.

    Therefore, the available research, studies, and surveys have positive and promising results. However, you must use CBG products with caution. Also, ensure you involve your doctor before you give it a try. As we look forward to more research on CBG and CBG-rich products, ensure you administer it with an open mind. Learn more about cbd for back pain

    How to Take CBG for Depression

    According to García-Gutiérrez et al. (2020), CBG's potential benefits effectively relieve stress and depression by improving sleep quality, reducing anxiety, and reducing muscle pains and inflammation. After all, survey respondents mentioned it as a better alternative to other traditional medicines. Importantly, if you are under certain depression medications or are a newbie to cannabis, we recommend you first consult your doctor.

    Always start with smaller doses as you progressively increase your dosage. This way, you allow your body to adjust accordingly as you monitor the progress. You may take it in the following forms and ways;

    • CBG Oil: The CBG is dissolved in a carrier oil, such as hemp seed oil or MCT oil, for enhanced absorption. As many people would opt, you can decide to place the CBG oil under your tongue. This is the quickest and most efficient way of absorbing the CBG oil in your body since the tinctures do not have to be gut-processed. Alternatively, you can decide to add it to your favorite beverage or cocktail and drink it up. Nonetheless, others may decide to vape the oil.

    If you love cooking or baking, you can add CBG oil to your favorite dish or baking ingredients. Give your snacks and backed goods some extra benefits. Moreover, a few tablespoons of CBG oil to your salads never hurt. Plus, you can add the CBG oil to your smoothie and enjoy the drink as you get the benefits of the CBG too. Remember, you can take the CBG oil as CBD oil for depression.

    • CBG Gummies: This is another great way of taking CBG edibles. You can ingest the gummy as you would any other candy. In most cases, the gummies are made with full-spectrum CBD oil in addition to the CBG present. Importantly, before purchasing a CBG gummy, go for full-spectrum, and choose from a trusted and reputable brand. In addition, check the ingredient list and carefully read the label to see what it contains to avoid allergies and sensitivities.

    Regardless of how you take CBD oil or gummies, it is important to begin in smaller doses. Various factors, such as weight, age, and metabolism, affect the outcome of CBG oil intake. Thus, there is no universal dosage. Additionally, even if you have used CBD oil before, remember that CBG is a different cannabinoid you are introducing to your system. So, the lower the dose, the better. You can gradually increase it depending on how your body responds.


    CBG is a sister cannabinoid to the popular CBD. These cannabinoids are increasing in popularity, thanks to their many health benefits. However, the available research on CBG is still limited. Thankfully, though, anecdotal evidence point out that it can help with depression. This, however, does not mean that one should stop using anti-depressants and switch to CBG without a trusted doctor's permission. Fortunately, there are numerous ways to take CBG for depression; remember to start small as you gradually increase the dosage. CBG is popular since it has no psychoactive effects. Furthermore, it also alleviates muscle and joint pains, inflammation, stress, and anxiety and improves sleep quality. Always ensure you purchase high-quality CBG oil from a reputable brand, and check the product label to ensure you aren't allergic to any ingredient used.


    Burstein, S. (2015). Cannabidiol (CBD) and its analogs: a review of their effects on inflammation. Bioorganic & medicinal chemistry, 23(7), 1377-1385.

    Dawson, D. A., & Persad, C. P. (2021). Targeting the Endocannabinoid System in the Treatment of ADHD. Genet Mol Med, 3(1), 1-7.

    García-Gutiérrez, M. S., Navarrete, F., Gasparyan, A., Austrich-Olivares, A., Sala, F., & Manzanares, J. (2020). Cannabidiol: a potential new alternative for treating anxiety, depression, and psychotic disorders. Biomolecules, 10(11), 1575

    Martinelli, G., Magnavacca, A., Fumagalli, M., DellʼAgli, M., Piazza, S., & Sangiovanni, E. (2021). Cannabis sativa and skin health: dissecting the role of phytocannabinoids. Planta Medica.


    Nicola Boulton
    Nicola Boulton

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