Your Cart is Empty

  • Add description, images, menus and links to your mega menu

  • A column with no settings can be used as a spacer

  • Link to your collections, sales and even external links

  • Add up to five columns

  • by Nicola Boulton January 16, 2023 5 min read

    How Long Does It Take for CBD Oil to Work for Pain?

    CBD oil is a food supplement designed by blending appropriate carrier oils like hemp seed and jojoba oil with quality hemp materials. The period it takes to work for pain depends on the consumption method. Here is a comprehensive explanation for this.

    CBD oil is a food supplement designed by blending appropriate carrier oils like hemp seed and jojoba oil with quality hemp materials. Previously, patients used over-the-counter painkillers to address pain issues. Unfortunately, these drugs are expensive and have several negative side effects.

    Cannabis experts have recently designed CBD oil. This product is an excellent deal for anyone looking for a safe and effective pain-relieving natural food supplement. Since it comes in bottles with pre-determined dosages, you can consume it either orally or sublingually. Learn more about cbd for neuropathy

    What Is CBD Oil?

    Wakshlag et al. (2020) defined CBD oil as a food supplement prepared by mixing appropriate base oils with hemp materials. Hemp and cannabis sativa (marijuana) are strains of the cannabis plant family. Reputable producers prefer using the former strain in manufacturing CBD products as it contains high cannabidiol. The latter counterpart has more tetrahydrocannabinol (THC) molecule that exceeds the 0.3% legal threshold.

    While cannabidiol is non-psychoactive, the THC molecule is recognized for its intoxicating effects. Despite that, it combines with other cannabis elements to generate an entourage effect. CBD oil prompts considerable health impacts partly due to its anti-inflammatory, anti-oxidative, analgesic, and antifungal properties.

     CBD constitutes proteins, essential oils, fatty acids, vitamins, and minerals which have significant health effects. It would help if you administered an appropriate CBD dosage to enjoy these potential therapeutic benefits. Thankfully, the product is easy to use as it comes pre-packed in bottles with various dosages. Unfortunately, some customers are repelled by the earthy and bitter taste of cannabidiol oil. They can overcome that by masking this undesirable taste by enriching their suitable foods with an appropriate product dosage.

    One can choose your convenient method to ensure the cannabinoids are conveyed into the bloodstream to produce the desired effects. Remember that the consumption method determines the period when CBD oil starts working. This aspect is well elaborated in the next section.

    How Long Does CBD Oil Take to Work for Pain?

    CBD intake techniques significantly affect the time cannabidiol oil takes to address pain. Singh et al. (2018) stated that most users need about 45-60 minutes to relieve pain, depending on the dosage consumed. To understand better, let’s investigate various consumption methods.

    Oral Consumption Method

    Cannabidiol oil consumed via food, capsules, or liquid passes through your digestive system. Its convenience greatly motivates consumers to keep getting their daily CBD dosage. In this method, you can take cannabidiol oil by directly putting drops in your mouth and then swallowing or incorporating it into your preferred foods and beverages.

    Whichever method you choose, the product must pass through the digestive system and liver before being released into the bloodstream. Though the oral method is suitable for certain clients, it might be inefficient for those anticipating the cannabidiol results instantly. This is because the digestion process takes time.

    The CBD oil is broken into smaller molecules in the digestive system, after which it enters the liver. This organ does the final digestion as the product must undergo the first-pass process. According to Biernacki et al. (2021),the liver has various enzymes that lessen CBD concentration before the active product portion penetrates the bloodstream, where it circulates throughout your body. Though it has low bioavailability, it takes about 1-2 hours for positive pain impacts to manifest after administering the product.

    Under the Tongue (sublingual) Method

    This method is more effective and reliable than the one above. For example, it has a greater bioavailability rate and shorter onset period. To administer CBD oil sublingually, place the correct oil drops beneath your tongue and hold it for approximately 60 seconds. During that period, the mucous membrane absorbs cannabinoids. After the set time, wash away the remainder or swallow, depending on your preference.

    The product does not penetrate the bloodstream through the digestive system. It rather absorbs through sublingual glands (mucous membranes). This method ensures that more cannabinoids reach the bloodstream within no time. Specifically, the positive pain impacts are experienced within 30 minutes after consumption, depending on the product dosage and body tolerance.

    Does CBD Oil Work for Pain?

    Many scientists report that cannabidiol oil produces results when it interacts with the endocannabinoid system (ECS). This complex system constitutes three principal components; endogenous cannabinoids, cannabinoid neurotransmitters (commonly CB1 and CB2), and enzymes. It controls various body processes such as pain perception, homeostasis (body balance), mood, energy levels, sleep, appetite, fertilization, and anxiety.

    The central nervous system refers to nerves enclosed within the human spinal cord and brain. It contains CB1 receptors, which serve vital purposes in cognitive and emotional signals of pain sensitivity and marijuana. Though CB2 neurotransmitters exist in the central nervous system, they predominantly occupy the peripheral nervous system. This system represents the nerves not enclosed within the human brain or spinal cord. Rather, they are mostly found in your arms and legs.

    The human body produces endogenous cannabinoids naturally. These endocannabinoids are synthesized by ECS whenever the body detects pain or inflammation. The ECS stability is affected whenever different stressors like pain, injuries, and inflammation afflict it. The phytocannabinoids empower the system to re-adjust itself and eliminate pain and other problems. Enzymes also participate in cannabinoid breakdown and utilization.

    According to Khaleghi (2020),cannabidiol interacts with body receptors and systems to relieve inflammation and pain-related problems. Its analgesic and anti-inflammatory properties fight pain and prevent nerve damage.


    Certainly, cannabidiol oil is an essential food supplement that promotes body wellness and health. Most customers are abandoning commercial painkillers because this natural supplement has tremendously impacted pain.

    It functions by interacting with the human endocannabinoid system that controls pain perception, mood, homeostasis, and fertilization. Specifically, the cannabinoids attach to endocannabinoid receptors which help the system to re-adjust, thus eliminating pain.

    The time these pain-relief effects manifest depends on the chosen CBD intake method. For example, the effects are felt within 30 minutes in the sublingual technique and 1-2 hours in the oral option. With that understanding, choose the method wisely.


    Biernacki, Jastrząb, & Skrzydlewska (2021). Changes in hepatic phospholipid metabolism in rats under UV irradiation and topically treated with cannabidiol. Antioxidants10(8), 1157.

    Khaleghi (2020). New arthritis foundation guidelines on CBD use could be the first of many more. Alternative therapies in health and medicine26, 8-11.

    Singh, Gillespie, & Harvey (2018). Intranasal Ketamine and Its Potential Role in Cancer‐Related Pain. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy38(3), 390-401.

    Wakshlag, Cital, Eaton, Prussin, & Hudalla (2020). Cannabinoid, terpene, and heavy metal analysis of 29 over-the-counter commercial veterinary hemp supplements. Veterinary Medicine: Research and Reports11, 45.

    Nicola Boulton
    Nicola Boulton

    Also in CBD and Medical Conditions

    What’s The Typical CBD Dosage
    What's The Typical CBD Dosage

    by Nicola Boulton September 02, 2023 10 min read

    Read More
    CBD for Tourette
    CBD for Tourette

    by Nicola Boulton September 02, 2023 10 min read

    Read More
    CBD for Sleep
    CBD for Sleep

    by Nicola Boulton September 02, 2023 9 min read

    Read More