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  • January 18, 2023 5 min read


    Cannabidiol (CBD) is an essential and non-psychoactive cannabis compound. Due to its anti-inflammatory properties, it shows promising results on pain-related problems like neuropathy.

    Cannabidiol (CBD) is an essential and non-psychoactive cannabis compound. It contains innumerable therapeutic benefits centred on its analgesic and anti-inflammatory properties. For this reason, many patients using over-the-counter drugs have reported undesirable side effects, making them look for alternatives. While doing that, cannabidiol products are the best options considering their pain-reducing and anti-inflammatory properties.

    Since neuropathy is a serious problem that affects multitudes globally, CBD-infused merchandise is the leading solution for anyone afflicted with that health issue. To experience pain relief, you should administer these products through your desirable consumption method.

    What is CBD?

    CBD is an essential and non-psychoactive cannabis compound. Its therapeutic potential is centred on its anti-inflammatory, anti-oxidative, and analgesic properties. Also, it interacts with the human endocannabinoid system to restore the body to homeostasis. Cannabis enthusiasts report significant effects after using cannabidiol for neuropathy.

    What causes neuropathy?

    According to Wang et al. (2016),neuropathy happens when nerves outside the spinal cord and brain (also called peripheral nerves) are negatively afflicted. Besides, this chronic issue can occur when your nervous system gets injured. Most patients suffering from this problem experience an electric shock-type sensation.

    Sadly, numerous people globally suffer from neuropathic pain. Many cases cause shooting, burning, weakness, numbness, or common pain around the feet. These problems arise spontaneously without a primary trigger. However, it can further prompt urinary and circulation digestion issues.

    Diabetes is among the major causes of neuropathy, where more than seventy per cent of diabetic people report painful symptoms. Therefore, everyone should control their blood sugar to decrease the chances of diabetic neuropathy and diabetes.

    Besides diabetes, several factors can contribute to neuropathy problems. These include traumatic injury, inadequate vitamin B12, alcoholism, chemotherapy, and nerve-injuring medication. Learn more about is cbd beneficial for athletes?

    How does cannabidiol for neuropathy work?

    Oil-based cannabidiol-infused topical products counter pain sensations emanating from the injured nerves. Consequently, the patient using cannabidiol for neuropathy gets relieved from various discomforts. Most consumers have reported positive impacts because cannabidiol contains anti-inflammatory and anti-oxidative properties. Moon et al. (2018)found that topical cannabidiol reduced inflammation and pain.

    In most instances, CBD works for neuropathy by interacting with the consumer's endocannabinoid system (ECS). Their interaction starts to adjust certain processes in your body to maintain good health. For example, Hryhorowicz et al. (2019) showed that ECS modulates several body reactions, including memory, appetite, pain sensitivity, energy levels, memory, immune response, fertilization, body equilibrium (homeostasis), appetite, and mood. This means it naturally constitutes two tremendous cannabidiol receptors, including CB1 and CB2.

    These two varieties serve different roles and are located in different body parts. For example, CB1 is more concentrated in the central nervous system, such as the spinal cord and brain. Besides, some of them are scattered in your lungs, reproductive organs, liver, urinary system, and retina.

    Furthermore, these neurotransmitters have crucial roles in pain sensitivity, motor regulation, memory processing, mood and sleep. Once stimulated, they cause several neuroprotective reactions. Since phytocannabinoids stimulate these neurotransmitters as they interact, it means that cannabidiol can counteract and treat several neurodegenerative problems, such as neuropathy, indirectly.

    Unlike CB1 varieties, CB2 receptors are mostly concentrated in the human immune system cells and the interrelated structures. When you stimulate them, they produce anti-inflammatory impulses that prevent nerve damage and pain sensation. Such potential is important in eradicating autoimmune problems. Examples are arthritis, Crohn’s disease, and inflammatory bowel disease (IBD).

    CBD interacts with body receptors indirectly to activate them. Besides interacting with these receptors, CBD can interrelate with certain body neurotransmitters, including 5-HT1A serotonin receptors. This unique type regulates feelings of well-being and emotional stability. According to Cahill et al. (2021),cannabidiol helps fight anxiety, nausea, and pain.

    How to consume CBD for neuropathy

    The cannabis industry is flooded with numerous cannabidiol products designed differently and consumed through unique consumption methods such as:


    This method involves administering cannabidiol topical products on the afflicted body part. Some products used in this way include CBD creams and lotions. When applying, massage the product into your skin until the cannabinoids penetrate dermal and sub-dermal skin layers. Doing so enables phytocannabinoids to counteract any pain-related problems like neuropathy and inflammation.


    Sublingual administration is one of the best cannabis consumption methods. It would be best to place CBD oil drops beneath your tongue here. This allows the cannabinoids to be absorbed into the bloodstream through sublingual glands. This method has a high bioavailability rate; hence manifests greater results within a short period. But for you to experience the relief, the cannabinoids must interact with the endocannabinoid system, as explained above.


    Vaping is significantly popular among cannabis enthusiasts due to its captivating experience. To vape, you should fill vaping devices with vape oil or CBD e-liquids. After that, pull in the vapour through the mouth of the device to enjoy the billows. While vaping, the cannabinoids enter the bloodstream through the lungs directly. This produces a great cannabidiol experience within a short period.


    This method involves putting drops of cannabidiol oil into the mouth, after which you swallow. Alternatively, you can enrich the sweetest foods and beverages with this product. This requires you to ingest the cannabidiol-enriched foods normally to enjoy the potential benefits associated with CBD.

    After consumption, the product passes through the digestive system and the liver for further digestion. This organ then releases the cannabinoids into the bloodstream. Though beneficial, this method delays the results, and its bioavailability rate is low.


    Having understood that about cannabidiol for neuropathy, now consider getting your desirable product formulation. Whichever you choose, the quality and your desired results are guaranteed. Most intake techniques allow cannabidiol to penetrate the bloodstream. Doing that enables it to interact with the endocannabinoid system, which regulates various body processes to restore body homeostasis.

    Many enthusiasts experiencing neuropathic pain have reported positive impacts after taking CBD-infused products. Therefore, you should not worry about the product's effectiveness and safety. First, however, purchase your desired options from reputable manufacturers. With that, your neuropathic problems with being eliminated within no time.


    Cahill, Lunn, Diaz, & Page (2021). Evaluation of patient-reported safety and efficacy of cannabis from a survey of medical cannabis patients in Canada. Frontiers in public health9, 626853.

    Hryhorowicz, Kaczmarek-Ryś, Andrzejewska, Staszak, Hryhorowicz, Korcz, & Słomski (2019). Allosteric modulation of cannabinoid receptor 1—Current challenges and future opportunities. International journal of molecular sciences20(23), 5874.

    Ma, Han, Wang, Ai, & Zheng (2016). Galectin-3 inhibition is associated with neuropathic pain attenuation after peripheral nerve injury. PLoS One11(2), e0148792.

    Moon, Buckley, & Mark (2018). Successful treatment of cannabinoid hyperemesis syndrome with topical capsaicin. ACG Case Reports Journal5.