CBD for Treating Leukemia

Did you know CBD may alleviate cancer symptoms? This is because of; the benefits of cannabidiol for leukemia, cannabidiol triggers apoptosis in cancer cells, cannabidiol nourishes healthy cells, risks and side effects of using cannabidiol for leukemia, and how to use cannabidiol for leukemia.

The cannabis compound THC has shown promise as a cancer treatment in several laboratory studies, animal models, and preclinical trials, including human participants. Cannabinoids not only have a curative effect on tumors but also help alleviate some unpleasant side effects associated with traditional treatments (e.g., chemotherapy and radiation). It should come as no surprise that an adding number of individuals are turning to CBD as a treatment for various types of illness, including leukemia, also known as the "silent killer." In what ways does CBD aid individuals who have leukemia? Is it a treatment that can be used on its own, or must it be combined with another?

This article will describe the mechanism of action and detail the most recent findings about cannabidiol and leukemia.

Benefits of Cannabidiol for Leukemia

It can alleviate the symptoms of various health issues because of CBD oil's high nutritional value, including leukemia. Terpenoids and minerals, full-spectrum hemp extracts contain very high concentrations of other beneficial compounds, including antioxidants, vitamins, proteins, and vital fatty acids. These substances may be good for your health.

 Seltzer et al. (2020) suggested that cannabidiol, or CBD, has anti-cancer properties, including the ability to inhibit the proliferation of cancer cells. However, it is essential to remember that there is a shortage of clinical trials in this field; the vast bulk of the study is derived from studies conducted on animal models and case reports involving humans.

Cannabidiol Triggers Apoptosis in Cancer Cells

Brock et al. (2019) stated that apoptosis is the process by which damaged cells in the body are eliminated naturally to aid in the upkeep of equilibrium. Leukemia is caused by the abnormal release of immature white blood cells, which clog up the lymphatic system and the circulation, making it hard for other types of vital blood cells to mature and proliferate. This condition is described in detail in the sections before this one.

CBD oil possesses powerful anti-cancer characteristics that have the potential to assist in lowering the rate at which cancerous cells spread. CBD signals the endocannabinoid system (ECS) of the body, telling it to manufacture more of its therapeutic messengers (endocannabinoids), which helps restore equilibrium in the body. CBD can eradicate cancer cells in human leukemia by triggering apoptosis.

Cannabinoids also affect the CB2 receptors, abundant throughout the immune system. This interaction enables the body to differentiate between healthy cells and ones that are harmful. It causes the formation of ceramide and sphingolipid, which in turn causes the death of sick cells.

The compound may also induce immunomodulatory effects because of cannabinoids' affinity for CB2 receptors, which enhance the functioning of the immune system. Cannabidiol, or CBD, acts as an antitumorigenic agent by preventing the reproduction of cancer cells. This can help keep the number of leukemia-affected cells under control and clears the way for creating healthy white blood cells, red blood cells, and platelets.

Cannabidiol Nourishes Healthy Cells

Farinon et al. (2020) suggested that cannabidiol is a rich supply of critical nutrients necessary for healthy cells' growth. Terpenoids, flavonoids, vitamins, proteins, and vital fatty acids are some examples of these components. The consumption of several chemicals can increase by consuming a full-spectrum cannabidiol extract in a carrier fat such as MCT oil.

Nutrients, especially amino acids and vitamins, are critical when producing healthy blood cells. Adding to the bioavailability of these high-quality nutrients may reduce the risk of cell mutation while preserving the health of healthy cells and protecting them from damage.

Cannabidiol oil might be able to provide the groundwork for the generation of healthy white cells by producing the ideal environment in which these cells might flourish.

Risks and Side Effects of Using Cannabidiol for Leukemia

Pellati et al.(2018)  revealed that cannabidiol is a recognized adaptogenic substance with few adverse effects. According to Taylor et al. (2015), cannabidiol is well tolerated in humans when administered 1,500 dosages daily over several weeks. CBD oil has no negative side effects when consumed at the recommended dosage levels. Large doses have the potential to cause the following adverse effects:

• The mouth is dry
• Appetite fluctuation
• Dizziness
• Fatigue
• Diarrhea

People with leukemia have the possibility of CBD-induced medication interactions. The enzyme system known as cytochrome p450, responsible for the metabolism of medication's active substances, is slowed down by CBD's presence. However, if you take any prescription that comes with a warning about the interaction with grapefruit, you shouldn't consume CBD oil simultaneously. Seek a medical professional's advice to reduce the chances of experiencing such things.

Cannabidiol for Leukemia

CBD is available in a wide variety of various formulations. It can alleviate the symptoms of various health issues, although it can be difficult to determine the optimal administration strategy. The following is a list of some of the most prevalent ways to consume CBD to treat leukemia:

Cannabidiol Oil

Cannabidiol oil is a sublingual product, which means that the cannabidiol extract is placed under the tongue and allowed to stay there for up to one minute before being swallowed. CBD oil is also known as cannabidiol (CBD). CBD can be absorbed into the bloodstream directly when it is administered sublingually. This method of administration. Compared to other methods that do not involve inhalation, this one is regarded as the most effective way to introduce cannabidiol into the system. Three different forms of sublingual CBD are available, including oil drops, tinctures, and sprays.

Cannabidiol Capsules Oral products, such as capsules, are the most common form of cannabidiol used by people constantly on the move. When you have a hectic lifestyle and do not have the time to measure out your doses with a dropper but would rather have a set amount of cannabidiol in each serving, capsules are a good alternative to oils that you can use. Because cannabidiol capsules are also odorless and tasteless, you won't have to worry about the botanical flavor lingering in your mouth after taking them. Capsules go through the digestive system first since they take longer to take effect than oils, between 40 and 90 minutes after application.

CBD edibles are becoming popular as the cannabinoid is added to various meals and beverages. You have a selection of options, including chewy candies, honey sticks, protein bars, chocolates, and beverages such as coffee or tea. One enjoyable way to consume CBD is through edibles; they have a delayed onset like capsules. They may lose some of their efficacy along the route to the bloodstream due to first-pass metabolism in the liver.

Spindle et al. (2020) proved that inhaling vaporized CBD from a CBD vape pen allows you to get CBD into your system. When you inhale CBD vapor, the compound is absorbed into the bloodstream through the lung tissue. This ensures that the compound's benefits will take effect quickly and that it will be readily available to the body. The vape pen heats the cannabidiol liquid to the point where it exhales cannabinoid-rich vapor, thereby preventing the liquid from combusting. A person can experience the benefits of vaping CBD within minutes, but they last between three and four hours.

Cannabidiol Topicals

When cannabidiol is applied topically, it interacts with the cannabinoid receptors found in the skin's epidermal layer. These receptors are located in the outermost layer of the skin. It is from this location that it creates its anti-inflammatory and analgesic properties, which contribute to a reduction in the amount of pain experienced by people with leukemia. Creams, balms, gels, lotions, and salves are the various forms of topicals; their absorption rate and the length of time their effects last varies depending on the preparation. People typically take them for skin care, but others believe they can also provide respite from the excruciating flare-ups that occur when leukemia is active.

Conclusion

CBD reduces feelings of nausea since it is the remedy for symptoms and side effects of leukemia and the treatments. CBD and other cannabinoids can help treat various cancers. However, there is still a lack of research on human trials, so medical professionals do not recommend using CBD as an alternative treatment for leukemia.

When looking at the various CBD products available, selecting a CBD oil of the highest possible quality from a manufacturer with a solid reputation is important. CBD products derived from hemp are classified as health supplements. Consult your primary care physician to obtain guidance regarding the appropriate intake method, CBD dosage, and any potential contraindications.

References

Brock, C. K., Wallin, S. T., Ruiz, O. E., Samms, K. M., Mandal, A., Sumner, E. A., & Eisenhoffer, G. T. (2019). Apoptotic Bodies From Dying Cells Induce Stem Cell Proliferation During Epithelial Tissue Maintenance. Nature Communications, 10(1), 1-11.

Farinon, B., Molinari, R., Costantini, L., & Merendino, N. (2020). The Seed Of Industrial Hemp (Cannabis Sativa L.): Nutritional Quality And Potential Functionality For Human Health And Nutrition. Nutrients, 12(7), 1935.

Pellati, F., Borgonetti, V., Brighenti, V., Biagi, M., Benvenuti, S., & Corsi, L. (2018). Cannabis Sativa L. And Nonpsychoactive Cannabinoids: Their Chemistry And Role Against Oxidative Stress, Inflammation, And Cancer. Biomed Research International, 2018.

Seltzer, E. S., Watters, A. K., Mackenzie Jr, D., Granat, L. M., & Zhang, D. (2020). Cannabidiol (CBD) Is A Promising Anti-Cancer Drug. Cancers, 12(11), 3203.

Taylor, L., Gidal, B., Blakey, G., Tayo, B., & Morrison, G. (2018). A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple-Dose, And Food Effect Trial Of The Safety, Tolerability, And Pharmacokinetics Of Highly Purified Cannabidiol In Healthy Subjects. CNS Drugs, 32(11), 1053-1067.