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  • by Nicola Boulton September 28, 2022 5 min read

    Does CBD Cream Work for Pain?

    Many individuals are curious about whether CBD creams relieve pain. This article explains how to use CBD cream, how CBD cream relieves pain, the legality of CBD creams, the side effects of using CBD creams, and finding the best CBD cream for pain.

    CBD, or cannabidiol, is a cannabinoid from hemp and marijuana plants. It does not get individuals high, unlike THC, which is prevalent in marijuana. CBD creams relieve pain by binding with cannabinoid receptors, a group of receptors in the body affected by both CBD and THC. There are two primary types of cannabinoid receptors in the body, CB1 and CB2. CB1 is mainly present in the central nervous system, while CB2 receptors are found in the peripheral nervous system. Surprisingly, the skin has been shown to have both CB1 and CB2 receptors. Scientists also discovered that while CBD controls and somewhat limits the actions of CB2 and CB1 receptors, THC may attach to and stimulate either receptor.

    CBD topicals, such as gels, lotions, creams, and roll-ons, boost wellbeing in particular regions to lessen pain. The right CBD topical is composed of organic CBD oil and includes essential oils and amino acids for skin strength and a chilly sensation.

    How To Use CBD Pain Cream

    Use enough CBD cream and apply it to the target area externally. Even as creams are absorbed through the skin, they can offer relief both on the skin's surface and in the muscles. The various creams are also well-known for promoting relaxation and improving sleep quality. Furthermore, they relieve chronic pain and inflammation.

    To maximize the benefits of the CBD product, it makes sense to approach pain in two distinct ways: Applying topical CBD creams enables individuals to treat any aching joints and muscles from the source. The absorbent structure of the skin allows CBD creams to soak in and start working instantly. Other organic components like menthol and eucalyptus improve the CBD cream’s natural pain-relieving abilities. After working out, individuals should apply CBD topical creams by massaging the target area. CBD cream will begin to relieve those sore joints and muscles within minutes.

    How Does CBD Cream For Pain Work?

    Utilizing CBD topical products enables individuals to experience the regionalized effects fairly rapidly as opposed to ingesting it, which can take anywhere between thirty minutes to three hours to take full effect.

    According to Baron (2018), CBD cream is an excellent choice for treating tightness, soreness, inflammation, and pain in particular body parts because of its fast absorption and inherent benefits. In a study with almost three hundred individuals who had osteoarthritis-related knee pain, researchers discovered that a topical synthesized CBD cream dramatically reduced individuals' severe pain. Three hundred milligrams of CBD cream were administered to these participants every day for ten weeks.

    According to Maida et al. (2017), topical CBD cream treatment considerably decreased pain in specific individuals with myofascial pain (regional tissue and muscle pain) and peripheral neuropathy, two disorders that harm the peripheral nervous system.

    How CBD Cream Relieves Pain

    The endocannabinoid system maintains a state of balance in the body. Furthermore, it is key in pain control, emotional response, and immune response.

    According to Mechoulam et al. (2013), both the peripheral and central nervous systems contain several endocannabinoid receptors. They alter pain receptors since they are located in the neurological system. Scientists claim that CBD cream encourages the system to utilize its endocannabinoids to suppress discomfort more efficiently. Researchers that have studied the benefits of CBD on chronic neuropathic pain have discovered that it also improves sleep, diminishes the psychological impact of the pain, and lessens its severity. Therefore, CBD is more efficient when applied topically than consumed orally. Further thorough studies must affirm CBD cream as a tried-and-true remedy for chronic pain, including rigorous clinical studies.

    Is CBD Legal?

    According to Sekar, K. & Pack A. (2019), the FDA has only authorized CBD for inclusion in a prescription medicine named Epidiolex. It helps children with rare forms of childhood epilepsy, like Lennox-Gastaut syndromes and Dravet syndrome. The FDA has recently sent threatening letters to businesses promoting unlicensed new CBD-containing medications since it does not acknowledge its usage in treating, diagnosing, or inhibiting any other condition.

    Side Effects of Using CBD Cream For Pain

    Even though CBD cream has many potential benefits, some individuals reported side effects, including interaction with other medicines, nausea, appetite, dry mouth, gastrointestinal issues, drowsiness, loss of appetite and weight, and other reported liver issues.

    Finding The Best CBD Cream for Anxiety

    Various customers can find merchandise on the market that provides several blends, adds natural extracts known to improve health, has different CBD levels, and has a range of flavors and smells. Additionally, individuals can combine CBD topical cream alongside alternative CBD products like candies or oils for improved effects and extra advantages like reduced anxiety and stress.

    Individuals who are new to CBD should begin with a lower dosage. Choose a soothing cream to aid in efficient post-workout recovery or a boosting CBD cream to give muscles a pre-workout jolt. Furthermore, a calming CBD topical cream is used for generalized muscular aches and standard treatment. Consider a CBD product with a higher concentration for inflammation or chronic pain. Various high-quality CBD products are available; individuals should try two or three to see which ones are more effective.

    What to consider while purchasing CBD creams

    • Read the customer reviews.
    • Read the product label, and ensure there are no harmful or allergic ingredients.
    • Contact customer support for further clarification.
    • Confirm the hemp source and the extraction method.
    • Ensure the product has undergone intensive independent third-party testing.


    Although it's still unclear if CBD topicals may provide effective pain treatment, most people claim that creams, salves, and lotions work well for various conditions. Individuals should choose a potent, full-spectrum CBD cream from a respected manufacturer that uses high-quality, organic components if they want the best therapeutic effects. Keep in mind that even the most reliable CBD companies are open regarding their products, providing detailed information on their websites regarding the locations of the products' cultivation and processing. Before attempting CBD, consult the doctor, and confirm the hemp source and the extraction method.


    Baron, E. P. (2018). Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and cannabis science. Headache: The Journal of Head and Face Pain58(7), 1139-1186.

    Maida, V., & Corban, J. (2017). Topical medical cannabis: a new treatment for wound pain—three cases of pyoderma gangrenosum. Journal of Pain and Symptom Management54(5), 732-736.

    Mechoulam, R., & Parker, L. A. (2013). The endocannabinoid system and the brain. Annu rev psychol64(1), 21-47.

    Sekar, K., & Pack, A. (2019). Epidiolex as adjunct therapy for treatment of refractory epilepsy: a comprehensive review with a focus on adverse effects. F1000Research8.

    Nicola Boulton
    Nicola Boulton

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