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  • by Nicola Boulton January 16, 2023 4 min read

    Here's How Long It Takes to Feel the Effects of CBD

    Are you curious how quickly you might expect to feel the effects of CBD oil? How long do the benefits of CBD oil last?"  This article addresses these concerns and explains how various intake techniques will affect your CBD effects differently.

    How long it takes for CBD oil to have an effect varies depending on several factors. Cannabidiol (CBD) modulates ECS and has over 65 molecular targets,  influencing various physiological and mental functions. It's hard to say how long it will take for CBD oil to affect anyone. Several variables might impact how long it takes for CBD oil to start having an effect. People are all distinct individuals with individual biochemical make-ups. People also have varied dietary preferences, habits, and health issues.

    What Happens When CBD Is Ingested?

    According to Chayasirisobhon (2020),CBD travels via the circulatory system and into the endocannabinoid system. Connecting cannabinoid receptors in the brain is the ECS, a network of neurotransmitters. CBD's cannabinoid receptors interact with those in the body. However, unlike THC, CBD does not have any intoxicating effects; hence it does not share any receptors with it. It won't have the same physiological impact. According to Corroon& Felice (2019),CBD also has indirect interactions with receptor proteins that aren't part of the ECS, such as the serotonin receptor 5-HT1A and the vanilloid receptor TRPV1. The activation of these extra biological pathways is likely responsible for CBD's putative anti-inflammatory and pain-relieving actions. It's complicated how CBD interacts with the human body. How and for how long this cannabinoid stays in your system depends on the manner of ingestion, the CBD product's quality, and your unique chemistry.

    How Quickly Do You React to CBD?

    According to Elsaid et al. (2019), the effects of CBD and how long it takes to feel them depend on the person taking it. A few factors can modify CBD's effects on the body, including:

    Individual Biological Variables

    How you react to CBD and how long it takes to take effect may be affected by factors such as your gender, health, weight, metabolism, and degree of experience.

    Method of Administration


    Drops of CBD oil are often taken orally. When you swallow the oil, the CBD will not enter your bloodstream immediately; instead, it travels through your digestive system and liver before entering your circulation. The "first pass effect" occurs when CBD molecules are digested in the liver. Enzymes lower the concentration of CBD in the liver before the remaining CBD is released into circulation and distributed throughout the body. The same rule holds while consuming CBD edibles. Suppose you're using CBD gummies or a few drops of CBD oil in your go-to dish; it goes through the same laborious process lowering CBD levels in circulation. Spindle et al. (2020) proved that CBD might take an hour or two to take effect when used orally.


    CBD oil is taken sublingually by inserting a few drops beneath the tongue and massaging them with the tongue for at least 30 seconds, after which they may be swallowed. Doing so will expedite CBD absorption since the mucous membranes in your mouth will absorb it directly into your circulation rather than relying on your digestive system and liver. The after-effects might hit you within seconds. According to Working (2022),CBD absorbed sublingually will begin to kick a few hours later, similar to the experience of consuming THC edibles. You should start to feel the effects within 30 minutes of sublingual dosing,. The duration of any effects you experience should be at least an hour, with a peak of around two hours.


    Try a little dosage first to get a feel for how CBD affects you. This allows you to ease into the process and understand how CBD will affect your body. However, you may only experience effects if you take an adequate amount.


    The effects of cannabidiol (CBD) products with a higher concentration can be more pronounced. Individuals starting with CBD should start with low concentrations or maintain a low dosage while using a higher-concentration product.

    Frequently Asked Questions About CBD Oil

    Does Using CBD Oil Have Any Effect?

    Dosage is conditional on the individual, the CBD oil's quality, and the chosen mode of administration. Ensure you buy CBD products from a reputable, licensed company that uses third-party lab testing.

    Is It Best to Do So While Full or Empty when Taking CBD Oil?

    Some CBD oil manufacturers claim that the effectiveness of their products is enhanced when taken in the morning on an empty stomach. While it is true, arguing this way dilutes the effect. CBD has fat soluble, which is broken down in the digestive tract before it can be absorbed. Taking CBD alongside substantial meals will boost its bioavailability, enabling more CBD to enter the body.

    How Often Should I Take CBD, and at What Time of Day?

    When to use CBD oil is not dependent on the time of day. Your work schedule should determine when you decide to utilize it. Ensures you take your supplements regularly and simultaneously each day.


    It might take CBD oil one minute to two hours to start having an impact. Although age, general health, lifestyle choices, and nutrition all have a role in the beginning and duration, the mode of ingestion is the most important. Sublingual administration offers the optimal balance of rapid onset, sustained benefits, and absorption. The benefits of sublingual CBD oil use typically kick in between 15 minutes to an hour after ingestion and may linger for as long as six hours. Never self-medicate; start at the low end of the dosage range, and don't expect CBD to work overnight; instead, discuss your CBD supplementation with your doctor. However, if your endocannabinoid system is impaired, CBD may require a longer time to address the cannabinoid shortages in your body.


    Chayasirisobhon, S. (2020). Mechanisms Of Action And Pharmacokinetics Of Cannabis. The Permanente Journal, 25, 1-3.

    Corroon, J., & Felice, J. F. (2019). The Endocannabinoid System And Its Modulation By Cannabidiol (CBD). Alternative Therapies In Health & Medicine, 25.

    Elsaid, S., Kloiber, S., & Le Foll, B. (2019). Effects Of Cannabidiol (CBD) In Neuropsychiatric Disorders: A Review Of Pre-Clinical And Clinical Findings. Progress In Molecular Biology And Translational Science, 167, 25-75.

    Working, W. S. C. S. (2022). How Much CBD Should I Take The First Time?. Sign, 62.

    Nicola Boulton
    Nicola Boulton

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