How Is CBD Metabolized? - Glow Bar London

September 06, 2022 6 min read

How Is CBD Metabolized?

Can CBD be metabolized? Herein is about how CBD is metabolized, including; CBD interacting with various body functions, the nervous system and CBD, and its impact on the endocannabinoid system.

CBD, or cannabidiol, is a cannabinoid found in cannabis. Unlike its better-known counterpart, THC (tetrahydrocannabinol), CBD is non-intoxicating and does not cause a euphoric "high." CBD has a wide range of potential medical applications and is being investigated for its potential to treat various medical conditions. CBD is metabolized in the body in a variety of ways using enzymes. CBD is metabolized in the body by a process called hydrolysis. CBD is broken down into two smaller molecules, CBD acid, and THC acid. These molecules are absorbed into the bloodstream and transported to the body's organs.

CBD Interaction with Various Body Functions

The human body is a complex system constantly interacting with the environment. When CBD is ingested, it is absorbed by the body and interacts with various systems, including the endocannabinoid, nervous, and immune systems.

CBD oil is metabolized in the liver. The liver enzymes break down the CBD oil into various metabolites. These metabolites are then circulated through the body. Some of the metabolites interact with the cannabinoid receptors in the body. Others are excreted in the urine or fecal matter.
The endocannabinoid system is responsible for regulating a variety of physiological processes, including appetite, pain sensation, mood, and memory. Muller & Reggio (2020) stated that CBD interacts with the endocannabinoid system by binding to cannabinoid receptors, which helps to regulate these processes.
The nervous system is responsible for transmitting signals between the brain and the rest of the body. CBD interacts with the nervous system by binding to serotonin receptors, which helps to regulate mood and anxiety.
The immune system is responsible for fighting off infection and protecting the body from disease. CBD interacts with the immune system by activating the immune response.
CBD is a safe and effective treatment for a variety of medical conditions. It is important to consult with a healthcare professional before starting CBD treatment.

The Nervous System and CBD

The human nervous system is an incredibly complex and intricate system that is responsible for controlling and regulating all the activities of the body. It consists of the central nervous system (CNS) and the peripheral nervous system (PNS). It comprises billions of nerve cells (neurons) that communicate with each other through electrical and chemical signals.
The CNS comprises the brain and the spinal cord, and the PNS consists of all the other nerves in the body. The PNS is further divided into the autonomic nervous system (ANS) and the somatic nervous system.
The autonomic nervous system controls all the body's involuntary activities, such as heart rate, breathing, digestion, and kidney function. The somatic nervous system controls the voluntary activities of the body, such as movement and sensation.
The human nervous system regulates many physiological processes, including appetite, mood, sleep, stress, and pain. It is also responsible for the coordination and control of all the activities of the body.
The endocannabinoid system is a physiological system that plays a role in the control of many activities of the body, including appetite, pain sensation, mood, and memory. The endocannabinoid system consists of cannabinoid receptors (CB1 and CB2), endocannabinoid molecules (endocannabinoids), and the enzymes that synthesize and degrade the endocannabinoids. CBD binds to cannabinoid receptors, and this interaction is thought to contribute to the beneficial effects of CBD.

Impact of CBD on the Endocannabinoid System

Endocannabinoids are lipid molecules produced in the body and are involved in various physiological processes, including appetite, pain-sensation, mood, and memory. CBD can activate the endocannabinoid system, which plays a role in regulating these processes. By activating the endocannabinoid system, CBD may help to reduce pain and inflammation, improve mood, and enhance cognitive function. CBD may also increase appetite and promote weight gain.

Cannabis oil comprises different compounds that work together to create therapeutic effects. One of these compounds is CBD or cannabidiol. CBD is a non-intoxicating cannabinoid that interacts with the endocannabinoid system, a network of receptors in the brain and throughout the body. CBD has many therapeutic benefits, including relief from anxiety, pain, and inflammation.
The endocannabinoid system is responsible for regulating a variety of physiological processes, including appetite, mood, memory, and pain sensations. When CBD interacts with the endocannabinoid system, it can help to restore balance and promote homeostasis. This is why CBD is such a promising treatment for various medical conditions.

Capodice & Kaplan (2021) discovered that the endocannabinoid system is also responsible for the psychoactive effects of cannabis. This is why THC, another compound found in cannabis oil, is also therapeutically beneficial. THC interacts with the endocannabinoid system differently than CBD and is responsible for the euphoric "high" associated with cannabis.
CBD has various therapeutic benefits and lacks psychoactive effects. CBD is becoming increasingly popular as a treatment for various medical conditions. CBD is safe and non-toxic and can be administered in various ways, including orally, sublingually, or topically. CBD is also available as an oil, which can be ingested or applied topically.

Immune System

Oláh et al. (2017) noted that CBD oil impacts the immune system.
It's important to understand that CBD is not a magic bullet. It won't cure every illness or make you invincible to infection. However, some evidence is that CBD may help support the immune system.

The human immune system is a complex network of tissues, cells, and organs that work together to protect the body against infection and disease. This system is constantly at work, identifying and destroying harmful bacteria, viruses, and other organisms. The immune system can also protect the body against cancer and other diseases.
The endocannabinoid system (ECS) regulates the immune system, which is responsible for mediating the body's response to cannabinoids. The ECS consists of cannabinoid receptors (CB1 and CB2) in the body and endocannabinoids anandamide and 2-arachidonoylglycerol (2-AG).
The ECS regulates the immune system. Cannabinoids, including CBD, stimulate the production of cytokines, proteins that help regulate the immune system. CBD blocks the activation of the NF-kB pathway, a protein that plays a role in inflammation and the immune response.
CBD may help to regulate the immune system and reduce inflammation. This could treat inflammation, such as autoimmune diseases, joint pain, and skin conditions.
Nichols & Kaplan (2020) stated that CBD might help regulate the inflammatory response. CBD can reduce inflammation in several tissues, including the brain, gut, and lung. This could help keep the immune system balanced and prevent it from overreacting.
CBD may also help promote a healthy balance of gut bacteria. The gut microbiome plays a key role in regulating the immune system. CBD has been shown to increase the abundance of beneficial bacteria in the gut, which could help to improve immune function.
CBD may also have anti-viral and anti-bacterial properties. This could help to protect the body from infection.
CBD may help to support the immune system in several ways. However, if you are interested in using CBD oil to boost your immune system, talk to your healthcare provider to see if it is right.

The metabolism of CBD is thought to be beneficial in treating several medical conditions. CBD acid is believed to have anti-inflammatory and analgesic properties, while THC acid has psychoactive properties. Cannabidiol is a compound found in the cannabis plant. CBD is one of the many cannabinoids, the chemical compounds found in cannabis. CBD is non-psychoactive and does not cause the "high" associated with marijuana. CBD has several potential health benefits, including relieving pain, reducing anxiety, and improving sleep. CBD is also thought to be beneficial in treating several medical conditions, including chronic pain, epilepsy, and multiple sclerosis.


Capodice, J. L., & Kaplan, S. A. (2021). The Endocannabinoid System, Cannabis, And Cannabidiol: Implications In Urology And Men's Health. Current Urology, 15(2), 95.

Muller, C., & Reggio, P. H. (2020). An Analysis Of The Putative CBD Binding Site In The Ionotropic Cannabinoid Receptors. Frontiers In Cellular Neuroscience, 14, 615811.

Nichols, J. M., & Kaplan, B. L. (2020). Cannabidiol regulates immune Responses. Cannabis And Cannabinoid Research, 5(1), 12-31.

Oláh, A., Szekanecz, Z., & Bíró, T. (2017). Targeting Cannabinoid Signaling In The Immune System: "High" -Ly Exciting Questions, Possibilities, And Challenges. Frontiers In Immunology, 8, 1487.