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  • by Nicola Boulton September 05, 2022 5 min read

    What Is CBDV? Is it Better than CBD?

    Cannabidiol, one of the main cannabinoids, has a non-psychoactive homolog called cannabidivarin (CBDV). It can be challenging to distinguish CBDV from CBD in lab tests because their molecular structures are similar. Herein is CBDV's legality of CBDV, exactly how CBDV works, and whether CBDV is better than CBD.

    You've likely heard about CBD if you've been using any of these products, but CBDv has been getting much attention lately. In the late 1970s, this cannabinoid was discovered, but only lately has it been studied. Cannabis products were prohibited in many jurisdictions, preventing research on this novel cannabinoid. However, recent research has shown that this cannabinoid may be used to treat various illnesses and improve the quality of life for those who suffer from them. How can you know whether CBDV is something you want to learn more about? Keep reading to learn more about the impacts that cannabinoids have on the body in the meantime.

    What Is CBDV?

    CBDv is a non-intoxicating molecule that does not provide the euphoric high often associated with cannabis with high THC concentrations. It shares a molecular structure with CBD. the major difference between the two is that the CBDv cannabinoid has a propyl chain. In contrast, the other has 30 stereoisomers and seven double-bond isomers. CBDV, in contrast to CBD, is present in considerably lower concentrations in the cannabis plant; hence its use for medicinal reasons is more costly. Indica Landrace strains are the best source of CBDV; however, certain Sativa strains may also contain the cannabinoid. A person's age, health, body sensitivity, and other variables all play a role in determining how much CBDv they should take. Even though this cannabinoid is natural, it is important to know the proper amount. Due to the research on CBDV, there are several studies on the possible medical ailments it might address.

    The Legality of CBDV (Cannabidivarin)

    The 2018 Farm Bill says that hemp plants and their byproducts that contain no more than 0.3 percent THC by dry weight may be produced and sold in the United States. An independent lab test should always be used when purchasing high-CBDV cannabis strains or CBDV-specific products. People don't anticipate CBDV to be prohibited since it is non-psychoactive and deemed safe and non-toxic.

    Is CBDV Better Than CBD?

    CBG is not "better" than CBD, but people never declare that any cannabinoid is "worse." CBD and CBDv are better at various things and are particularly effective when used together. According to Morano et al. (2020), CBDV  typically offers more cheery or powerful outcomes than CBD while being completely non-intoxicating. There have been a lot of studies on CBDv's potential digestive and antibacterial advantages, two areas where CBD hasn't been a primary focus.

    How Does CBDV Work?

    If you're curious about CBDv, you're probably also interested in learning how it works. According to Iannotti et al. (2014), the Endocannabinoid System and TRP Ion Channels, two important systems that CBDv and CBD share, are not only structurally similar but also act similarly. The study above suggested that  Messages from the ECS are sent back to the neurons that transmit the information from various organs to the brain. According to Goadsby et al. (2017), many unpleasant symptoms, including anxiety, migraines, sleeplessness, and menstrual cramps, may be caused by a malfunction in the ECS. Indirectly stimulating the endocannabinoid system, this cannabinoid enhances and reduces receptor responsiveness.

    Axonal Ion Pathways

    Ion Channels are sensors in the body that notify the nervous system when chemicals and severe temperatures are present. Spicing up your diet might also stimulate these pathways. According to Rosenberg et al. (2015), CBDV and CBD can promote certain TRP channels, making them more effective at treating migraines, neuropathic pain, and epilepsy, among other conditions. Maroon & Bost (2018) revealed that TRP channels in the brain are more strongly affected by the natural substance than by the majority of hemp-derived cannabinoids.

    What Can CBDV Be Used for?

    It is possible to use CBDv in a vape cartridge via the oil or extract in the same way CBD products are used, including adding it to oils, tinctures, and edibles. It contains less than 0.3 percent THC, and this cannabinoid is allowed to buy and consumed under the terms of the 2018 Farm Bill. It has medical advantages. Although CBD and THC goods have potency, CBDV products also have potency, and even if the product is natural, you must be cautious about the correct dose. However, it's also safe to use if you get it from a reputable brand or supplier. One may use CBDV products for medicinal reasons, but if you're already taking other drugs, it's best to see a doctor before using CBDV. Regardless of what cannabis you're taking, you need to know the correct dose, examine the product's contents, and check the seller's reputation. In the next section, let's look at the medicinal consequences of CBDV.

    CBD and CBDV are chemically identical, except for CBDV's propyl chain, yet both have shown an anticonvulsant effect in tests. THC gives consumers the nice buzz they want by connecting to the CB1 and CB2 receptors, as is well known. According to De Petrocellis et al. (2011), CBDV impacts the capsaicin receptor TRPV1. Dos Santos et al. (2015) suggested that CBDV has anti-epileptic characteristics and is often utilized in the medical profession to treat seizures. Activating TRPA1 and TRPV2 ion channels lowers neuronal hyperexcitability, lessening epileptic activity. Baron (2018) discovered that CBDV has many of the same advantages as CBD, including promoting relaxation and muscle recovery, reducing chronic pain, lowering stress levels, and enhancing sleep quality, among other things. CBDV is better for migraines, neuropathic pain, seizures, neuropathic pain, and other related illnesses.


    It is important to understand that the therapeutic benefits produced by CBDV and CBD are strikingly comparable. They suggest that both cannabinoids might be a great success in the medical business. Nearly comparable in many ways to cannabidiol, but with certain distinct qualities that make it stand out. People with neurological diseases, epilepsy, and associated seizures benefit greatly from CBDV. However, CBDV's anticonvulsant, ant-epileptic, and anti-nausea characteristics require additional investigation. CBDV offers a wide range of characteristics. A person's age, health, body sensitivity, and other variables all play a role in determining how much CBDV they should take. Research into CBDV's latent medical potential will be necessary to put this cannabinoid into use more quickly and effectively.


    Baron, E. P. (2018). Medicinal Properties Of Cannabinoids, Terpenes, And Flavonoids In Cannabis, And Benefits In Migraine, Headache, And Pain: An Update On Current Evidence And Cannabis Science. Headache: The Journal Of Head And Face Pain, 58(7), 1139-1186.

    De Petrocellis, L., Ligresti, A., Moriello, A. S., Allarà, M., Bisogno, T., Petrosino, S., ... & Di Marzo, V. (2011). Effects Of Cannabinoids And Cannabinoid‐Enriched Cannabis Extract On Trp Channels And Endocannabinoid Metabolic Enzymes. British Journal Of Pharmacology, 163(7), 1479-1494.

    Dos Santos, R. G., Hallak, J. E. C., Leite, J. P., Zuardi, A. W., & Crippa, J. A. S. (2015). Phytocannabinoids And Epilepsy. Journal Of Clinical Pharmacy And Therapeutics, 40(2), 135-143.

    Goadsby, P. J., Holland, P. R., Martins-Oliveira, M., Hoffmann, J., Schankin, C., & Akerman, S. (2017). Pathophysiology Of Migraine: A Disorder Of Sensory Processing. Physiological Reviews.

    Iannotti, F. A., Hill, C. L., Leo, A., Alhusaini, A., Soubrane, C., Mazzarella, E., ... & Stephens, G. J. (2014). Nonpsychotropic Plant Cannabinoids, Cannabidivarin (Cbdv), And Cannabidiol (Cbd) Activate And Desensitize Transient Receptor Potential Vanilloid 1 (Trpv1) Channels In Vitro: Potential For The Treatment Of Neuronal Hyperexcitability. Acs Chemical Neuroscience, 5(11), 1131-1141.

    Maroon, J., & Bost, J. (2018). Review Of The Neurological Benefits Of Phytocannabinoids. Surgical Neurology International, 9.

    Morano, A., Fanella, M., Albini, M., Cifelli, P., Palma, E., Giallonardo, A. T., & Di Bonaventura, C. (2020). Cannabinoids In The Treatment Of Epilepsy: Current Status And Prospects. Neuropsychiatric Disease And Treatment, 16, 381.

    Nicola Boulton
    Nicola Boulton

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