What Is the Difference Between Cannabigerol and Cannabidiol? - Glow Bar London

September 15, 2022 5 min read

What Is the Difference Between Cannabigerol and Cannabidiol?

CBD and  CBG  have more similarities; the only difference is based on the quantities in the plant.

CBD and CBG are derived from cannabis and hemp plant. They are two of the three common cannabinoids; the other one is THC. The three cannabinoids only differ in quantities. In the plant extract, the CBG amount is 1%, whereas CBD ranges from 20% to 25% and THC from 25% to 30%. CBG is in smaller quantities in the full-grown plant than THC and CBD. This is because CBGA, the acidic form of CBG, is converted to CBD and THC as the plant grows.   CBD and  CBG  have more similarities; the only difference is based on the quantities in the plant.


CBD and CBD are cannabis compound which does not have a psychoactive effect like THC. According to Watt & Karl (2017), THC, marijuana's most common compound, has a psychoactive effect, which causes a high feeling in the user. Marijuana contains more THC, while hemp contains CBD. Therefore, CBD derived from hemp is legalized by the Food and Drug Administration since it is considered safe for human consumption and cannot intoxicate the user.

CBG is rare, which is the reason why it's expensive. However, its popularity follows the health benefits associated with its health benefits. You can benefit from CBD and CBG by using the same plant extract. For example, the broad-spectrum CBD contains all cannabinoids, terpenes, and flavonoids except THC.

How CBG And CBD Work

CBG and CBD work by interacting with the cannabinoid receptors found in the body. The cannabinoid receptors are found in the central nervous system and are thus present in different body parts, including the brain, skin, and nerves. CBD and CBG do not have a psychoactive effect. Therefore they cannot affect the mental state of the user.

The body contains two major cannabinoid receptors known as CB1 and CB2 receptors. CBG and CBD bind the CB1 and CB2 receptors and thus provide the desired r effect to the body. Unlike THC acts on CB1 receptors alone to cause hallucination. CB1 receptors are in the brain and nerves, while CB2 receptors are in the immune system and the rest of the body. Despite the from-go CBG and CBD administration, they should act on the c receptors.

How CBG And CBG Are Made

CBD and CBG   are derived from the cannabis plant. There are many similarities and differences in the amount extracted from the plant. CBG and CBD are mainly found in the oil because they are mixed with the carrier oils such as coconut and hempseed oil after extraction.  CBD and CBD are all made form the cannabigerol acid CBGA.

Young cannabis plants have more CBGA, and thus the plants have more CBG. However, CBGA is converted to THC and CBD when the plants grow. This is why fully grown cannabis plants have more of the two compounds. Although CBG oil is rare and expensive, you are not limited from benefiting from it. You can benefit from CBG and CBD oil by using broad-spectrum CBD.

The broad-spectrum CBD which all the cannabinoids, flavonoids, and terpenes except THC. Many people tend to avoid THC in their products, but research shows that all the compounds work together for the well-being of the body; by complementing each other's effects and potency.

CBD and CBD are extracted from the plant using chemicals and CO2. Rochfort et al. (2020) showed that CO2 is the bests method of extracting cannabinoids since it does not expose the compound to harsh chemicals which contaminate the product.

How to Use CBD and CBG

CBD and CBG are found in different forms. Since they are legalized, they are infused in many products. CBG is most used in its oil form due to scarcity; however, it can be infused in any product based on the reason for taking the cannabinoid compound. The most common way of benefiting from CBG is broad-spectrum CBD.

This type of CBD is infused in different products, including edibles such as gummies, topicals, vapes, and sublingual.

Edibles: CBD edibles such as gummies are good and the most discrete way of taking CBD. It is also the bests for beginners. They take some time for the effect to reach the surface, but you can benefit from it for a long.

Topicals are designed to be used on the skin surface. They interact with the cannabinoid receptors in the skin to provide relief. They are mostly good for pin relief since the compound is gentle enough to be applied directly to the affected area, thus easing the pain.

Vapes are used in cartridges with batteries; when exposed to a certain temperature, the vape juice becomes vapor directly inhaled into0 the lungs. CBD taken by vaping has a fast effect due to its high bioavailability.

Similarities of CBG aAnd CBD

  • They both work by binding the CB1 and CB2 receptors
  • They do not have a psychoactive effect; they cannot alter the consumer's mental state.

 Health Benefits of CBG and CBD


Many health conditions are characterized by inflammation, either internal or external. CBD and CBG are widely used due to their ability to reduce swelling. According to McDonnell et al. (2020), CBG can treat inflammatory bowel diseases since it has an anti-inflammatory effect. The condition is characterized by severe inflammation of the bowel. The condition is incurable; however, studies show that CBG can help reduce swelling and pain; patients showed significant change after using it.


Gildea et al. (2022) noted that CBD could help treat bacterial and fungal infections due to its anti-bacterial and fungal properties. CBD and CBG are also infused in skin care products to treat different skin infections, including psoriasis. The compounds treat and prevent the infection and soothe and relax the body and mind.

 Pain Relief

 Pain is inevitable; thus, most people experience it at some point in life. Pain can affect your daily activities and productivity. It also can impact your sleep. Many painkillers can help relieve pain but tend to have diverse side effects. Überall (2020) revealed that CBD and CBG could help reduce chronic and acute pain by relaxing and soothing the body.


CBD, THC, and CBG are the most common cannabinoids. CBG is found in fewer quantities, making it rare and expensive. This has made cannabis farmers cross breed and adopts genetic manipulation to produce more CBG. THC and CBD are products of CBGA, an acidic compound of CBG. Therefore, CBG is in high amounts in the young plant compared to fully grown plants when the compound is converted to   THC and CBD. CBD and CBD can help reduce inflammation, treat bacterial and fungal effects, and relieve pain. They both interact with the cannabinoid receptors and have no mental alteration abilities.


Aqawi, M., Sionov, R. V., Gallily, R., Friedman, M., & Steinberg, D. (2021). Anti-Bacterial Properties Of Cannabigerol Toward Streptococcus Mutans. Frontiers In Microbiology, 12, 656471.

Mcdonnell, M., Harris, R. J., Borca, F., Mills, T., Downey, L., Dharmasiri, S., ... & Gwiggner, M. (2020). High Incidence Of Glucocorticoid-Induced Hyperglycemia In Inflammatory Bowel Disease: Metabolic And Clinical Predictors Identified By Machine Learning. BMJ Open Gastroenterology, 7(1), E000532.

Rochfort, S., Isbel, A., Ezernieks, V., Elkins, A., Vincent, D., Deseo, M. A., & Spangenberg, G. C. (2020). The Utilization Of Design Of Experiments Approaches To Optimize Supercritical Fluid Extraction Of Medicinal Cannabis. Scientific Reports, 10(1), 1-7.

Watt, G., & Karl, T. (2017). In Vivo Evidence For Therapeutic Properties Of Cannabidiol (CBD) For Alzheimer's Disease. Frontiers In Pharmacology, 8, 20.