Is CBD Oil Useful in Kidney Disease Management?

Kidney disease management is seen to affect various individuals across the world. With many dwelling on medication, some have been seen to dwell on alternative interventions like CBD oil and related products. This article explains whether CBD oil is used in managing kidney diseases, among other related aspects.

Introduction

Legalizing hemp products in the United States allowed various individuals and companies to produce and consume hemp-related products. CBD oil is one of the products that many individuals adopt across the world. CBD is extracted from the hemp plant legally accepted across the United States as it contains less amount of THC, which is intoxicating and psychoactive. The CBD extracted from hemp is associated with various therapeutic benefits like pain management, reducing inflammation, and reducing anxiety and depression. CBD oil can be consumed through ingestion, sublingually and topically. The products should contain no more than 0.3% THC per FDA regulations. One should be keen on the dosage, and the amount of product they consume as overdosing can result in mild side effects and make an individual uncomfortable.

What Is CBD Oil

CBD oil is obtained from the combination of CBD extract and various oil. Some of the oils that an individual can use in making CBD oil are MCT oil and Olive oil. Mixing the oil with the CBD extract helps to increase the product's bioavailability and effectiveness. Individuals are advised to check on the dosages and instructions provided to them by the physician. Consuming CBD oil by an individual makes them feel relaxed. It is a natural product that is non-intoxicating and non-psychoactive. Not all individuals are comfortable with THC's intoxicating effects, and CBD is the best option. Oberbarnscheidt & Miller (2020) stated that CBD oil is found in various types depending on the ingredients contained within the product. In the market, one can access CBD isolate, Full spectrum CBD oil, and broad-spectrum CBD oil. Each type of oil has different effects and abilities when consumed by an individual.

CBD Oil and Kidney Disease Management

The kidneys are among the organs in the body where the CB1 and CB2 receptors are expressed. Consumption of CBD oil can have beneficial and harmful effects on the functioning of the kidney. Patients with pre-existing kidney conditions can benefit from CBD oil when used per the physician and the instructed dosages.Ritter et al. (2016) explained that the endocannabinoid system plays a critical role in renal homeostasis. It is seen to help control renal hemodynamics and tubular sodium reabsorption in various parts by activating CB1 receptors. In an individual, when CBD oil is consumed, the CBD is seen to interact with the CB1 receptors, thus activation of distinct pathways in the mesangial cells of the glomerulus and the thick ascending limb of the Henle. Lafaye et al. (2022) explained that the consumption of CBD oil is seen to have beneficial aspects as it aids in treating various symptoms of advanced kidney disease and helps in end-stage renal disease, which may include pain adjuvant, thus reducing the need for opioids. Healthy individual kidneys are not affected by the consumption of CBD oil. Individuals with chronic kidney disease are closely checked on the consumption of CBD oil as it can affect renal functions in one way or another; thus, they are advised to consume the lowest dosages of CBD oil and avoid smoking CBD-related products. When one consumes CBD Oil, it can delay the transplant candidate in need of a kidney transplant or aid in the ineligibility of the process. Thangapandiya et al. (2019)explained consumption of CBD oil by an individual can help reduce oxidative stress, inflammation of the kidney, and nephrocity, which is kidney damage from drugs or toxins. The interaction of the endocannabinoid system receptors and CBD oil also helps regulate the blood flow and scarring of renal fibrosis.

Factors To Consider When Purchasing CBD Oil for Kidney Disease Management

Purchasing CBD oil for kidney disease management is important as the CBD oil market, and related products are highly unregulated. Some of the factors that individuals should consider are;

Source of the CBD

The source of CBD used in the treatment of kidney disease is important. CBD should be organically and naturally obtained. Not all CBD oil in the market is legitimate, as some are inorganically sourced, making them unfit for human consumption.

Purpose of the CBD oil

One can make the purchase depending on the purpose. With various types of CBD products in the market, a person can make a purchase depending on the ability or intensity of the condition to be treated.

Manufacturer

Before making the purchase, check the manufacturer of the CBD oil. Not all companies that produce CBD oil are legitimate. The CB market is highly unregulated, and one is advised to check for quality products. It is done by checking on customers' reviews and feedback.

Price

The price of CBD oil in the market varies from one place to another. The difference in the prices can result from a difference in potency and milligrams. Also, the quality of the product can bring variance in the prices.

THC Levels

The Farm Bill signed in 2018 allowed CBD products with no more than 0.3% THC levels. The prices can vary as per the CBD levelsand depending on the state that one is coming from. Some states allow the consumption of marijuana products with high THC amounts. It can bring variance; thus, one should be keen when purchasing.

Conclusion

Physicians advise individuals to be keen on the number of dosages they need to consume CBD oil, especially for individuals with chronic kidney disease and kidney failure. CBD oil is safe for consumption and legally accepted, and when consumed, it is seen to affect individuals differently. Individuals with kidney diseases are advised not to consume a large amount of CBD oil as it can affect their health. A healthy individual with no kidney disease is not affected by CBD oil. Some side effects of CBD oil includedrowsiness, fatigue, and weight loss. One should be keen and follow the doctors’ instructions adosage to prevent any adverse effects.

Reference

Lafaye, G., Karila, L., Blecha, L., & Benyamina, A. (2022). Cannabis, cannabinoids, and health. Dialogues in clinical neuroscience.

Oberbarnscheidt, T., & Miller, N. S. (2020). The impact of cannabidiol on psychiatric and medical conditions. Journal of clinical medicine research, 12(7), 393.

Ritter, J. K., Li, G., Xia, M., & Boini, K. (2016). Anandamide and its metabolites: what are their roles in the kidney? Frontiers in bioscience (Scholar edition), 8, 264.

Thangapandiyan, S., Ramesh, M., Miltonprabu, S., Hema, T., Jothi, G. B., & Nandhini, V. (2019). Sulforaphane potentially attenuates arsenic-induced nephrotoxicity via the PI3K/Akt/Nrf2 pathway in albino Wistar rats. Environmental Science and Pollution Research, 26(12), 12247-12263.