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  • by Nicola Boulton January 13, 2023 4 min read

    What Are the Side Effects of CBD Oil?

    Even though CBD is considered safe, some users report experiencing certain side effects, especially after consuming high amounts. This blog discusses the side effects of CBD oil, including dry mouth, fatigue, diarrhoea, and nausea. Herein, you will also learn how to prevent these effects.

    CBD (cannabidiol) oil has gained immense popularity in the health and wellness world. This compound is one of the major active ingredients in the cannabis plant. Unlike tetrahydrocannabinol (THC)- another prevalent cannabinoid in the cannabis plant, it is non-psychoactive. CBD is available in multiple formulations, including oils, tinctures, vapes, edibles, and topicals. CBD oil boasts various benefits, such as reducing anxiety, improving sleep quality and quantity, counteracting cancer-related symptoms, and alleviating pain and inflammation. However, like other medications and supplements, it has downsides when taken in large amounts, as discussed in this article.

    What Are the Side Effects of CBD Oil?

    CBD Oil Side Effects

    CBD oil can lead to multiple side effects when overdosed. Knowing a product's side effects beforehand helps you manage your routine more effectively. Some of the side effects of CBD oil include the following:

    Dry Mouth

    Liu & Tina (2019) noted that a dry mouth as a side effect of CBD does not symbolize dehydration, as most people presume. Since the mouth has cannabinoid glands, consuming CBD oil alters saliva production, leading to dryness. For newbies, it is recommended to increase your water intake if you experience dry mouth after consuming CBD oil, or you might have to be patient enough until it leaves the system fully.


    Mathur et al. (2020) noted that tiredness is one of CBD oil's most common adverse effects. Improving sleep quality and quantity is one of the many reasons people take CBD oil. Various users saw fatigue as a welcoming side effect of taking CBD oil since they get to fall asleep quickly, symbolising that the cannabinoid works effectively. However, taking more than the recommended amount of CBD oil can cause grogginess, affecting productivity. If taking CBD oil for any sleeping condition, consume it at night.

    Changes in Appetite

    Some ingredients used to manufacture CBD oil may boost an individual's appetite, while others may subside it. This effect varies per individual since everyone has a unique body chemistry. A change in appetite should not be one of your major concerns since once the chemical compound exits your system, your body will return to its normal state.


    Diarrhoea is one of the most prevalent side effects of taking CBD oil. Users may experience diarrhoea because of various reasons. It may be because you've taken a high amount, making it difficult for your system to digest. Also, your body may detect an unfamiliar product, making the stomach react unexpectedly.

    Change inWeight

    Appetite and weight are directly related. Since CBD oil affects appetite negatively or positively, it automatically causes a weight shift.


    Dizziness is normally experienced when an individual overdoses on a substance. Land et al. (2020)noted that one might experience dizziness after taking CBD oil since the body receptors try to tolerate the accumulating CBD compound.


    Nausea is a common side effect, especially among beginners. Since they are trying to incorporate CBD into theirdaily supplement regime, it is normal for their body receptors to try and adapt to the foreign compound. Grimison et al. (2020) suggested that this may result in stomach irritation making an individual nauseatic.

    How to Prevent CBD Oil Side Effects

    Consume the Required Amount

    Most adverse effects of CBD oil are normally experienced when consumed in high amounts. So, it is best to consume the recommended amount. If you do not have a doctor's recommendation, begin with a small amount and gradually work your way up. You should also follow the manufacturers' guidelines. Use the product as recommended, and seek medical attention instantly if you experience any unwanted reaction.

    Avoid Taking It with Other Medications

    Like most prescribed drugs, CBD oil is broken down in the liver. Consuming CBD oil and other medications may overwork the liver, leaving high amounts of the medication in your system, which is toxic. Mixing CBD oil and other medications may heighten its side effects. So, before taking CBD oil while on other medications, it is important to talk to a doctor first.

    Buy from a Reputable Brand

    High-quality products rarely cause any side effects, unlike low-quality products. Since the CBD market is flooded with untrustworthy and fraudulent brands, it is important to purchase the product only from a trustworthy and reputable brand to be safer.

    Below are various factors to look out for in a brand before purchasing its product:

    CBD Source

    Only purchase hemp-based CBD oil. The hemp plant contains high levels of CBD and low amounts of THC. So you do not have to worry about any mind-altering effects. Additionally, ensure that organic cultivating techniques were utilised since hemp plants absorb everything in the soil.

    Lab Reports

    A trustworthy company always provides its users with proof of third-party lab test reports and a certificate of the analysis report. These reports confirm the products' safety and quality. A COA outlines the product's cannabinoid content level and the presence of any toxic material, such as pesticides.


    Individuals take CBD oil for various purposes, such as alleviating anxiety, reducing pain, and improving sleep quality and quantity. Like multiple substances, CBD oil may cause side effects mostly when taken in high amounts. Some side effects of CBD oil include; diarrhoea, fatigue, changes in appetite and weight, dry mouth, and nausea. To counteract these effects, there are various factors to consider, such as taking the right amount, purchasing high-quality CBD oil, and not mixing CBD oil with certain medications, especially blood thinners. Talking to a medical professional before delving into the CBD world is important.


    Grimison, P., Mersiades, A., Kirby, A., Lintzeris, N., Morton, R., Haber, P., ... &Stockler, M. (2020). Oral THC: CBD cannabis extract for refractory chemotherapy-induced nausea and vomiting: a randomised, placebo-controlled, phase II crossover trial. Annals of Oncology31(11), 1553-1560.

    Land, M. H., MacNair, L., Thomas, B. F., Peters, E. N., & Bonn-Miller, M. O. (2020). Possible Drug–Drug Interactions Between Cannabinoids and Candidate COVID-19 Drugs. Cannabis and Cannabinoid Research5(4), 340-343.

    Liu, T. (2019). What is CBD Oil? Learn the Facts: Uses, Benefits and Side Effects.

    Mathur, K., Vuppalanchi, V., Gelow, K., Vuppalanchi, R., &Lammert, C. (2020). Cannabidiol (CBD) consumption and perceived impact on extrahepatic symptoms in patients with autoimmune hepatitis. Digestive Diseases and Sciences65(1), 322-328.

    Nicola Boulton
    Nicola Boulton

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