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  • by Nicola Boulton August 26, 2022 5 min read

    CBD for Gut Health

    During digestion, various mechanical and biological processes occur in the digestive system. Your gut health determines how efficiently your gut functions. The overall gut health and the benefits of CBD and THC are discussed below.

    It's a common misconception that the gastrointestinal system (GI system, often known as the gut) has one function: food digestion. However, it is capable of much more. It would help if you took good care of your stomach to work efficiently. A novel approach may be to use CBD to improve gastrointestinal health.

    Various digestive problems affect several people all over the globe. These disorders' intensity opens the door for more serious health problems. Having a healthy digestive tract can amazingly extend your lifespan.

    Gut Health

    Understanding the gut flora is essential for understanding the health benefits of cannabidiol (CBD). In this fascinating area, billions of viruses, bacteria, and fungi live in perfect harmony with one another.

    Bacteria in the Intestine

    According to Rowland et al. (2018), food digestion and the absorption of nutrients are two of the most important roles played by this microbiome. In addition, it is the primary source of most of the brain's neurotransmitters. Moreover, the gut microbiota influences cognitive and physiological functions daily, including the immune system. Having a healthy gut microbiota is essential to the proper functioning of all of your body's functions. On the other hand, several serious health issues may develop if your gut health declines, and this sudden decline is known as dysbiosis.

    Maintaining a healthy digestive system is important for this same reason. There are several benefits to having a healthy digestive system, including a healthier body and heart. Furthermore, several people in the United States are concerned about contracting heart disease, and many suffer from arterial stiffening.

    The Digestive System

    According to Marcon et al. (2021), having a healthy gut improves cardiovascular health. Jadoon et al. (2017) suggested that CBD increases your HDL cholesterol, improving your digestive health and lowering your heart disease risk.

    Gut health is crucial for a variety of other reasons. An overabundance of harmful bacteria in the stomach may also contribute to weight gain. At the end of this chain reaction is the development of heart disease and other serious health conditions. Trimethylamine N-oxide (TMAO) is a compound produced by harmful bacteria in the stomach that may clog arteries and cause strokes.

    At least one research has shown that a healthy digestive system may help avoid coronary artery disease. Your gut health also influences your mental wellness. Messages from the brain go down the vagus nerve to the intestines, where they are processed. According to Clarke et al. (2014), a key neurotransmitter that affects mental well-being is serotonin, produced by the gut's beneficial bacteria. One may reduce stress and anxiety levels by maintaining a healthy intestinal flora.

    CBD and THC Health Benefits

    The cannabinoid compounds THC and CBD may be obtained from the cannabis plant. There's much more to cannabis than the flowers, leaves, and buds. Among the several cannabinoids, tetrahydrocannabinol (THC) is the one most closely connected with medicinal marijuana's intoxicating high. There are more medicinal advantages to CBD (Cannabidiol) than to THC (Tetrahydrocannabinol), such as treating inflammatory bowel disease and chronic pain and boosting memory and brain function. Endocannabinoids and CBD share several characteristics. An endocannabinoid system naturally exists in our bodies. This mechanism produces endocannabinoids. Cannabinoid-like endocannabinoids are present in various products, including CBD, medicinal cannabis, and recreational pot.

    The ECS

    Both cannabidiol (CBD) and naturally occurring endocannabinoids (ECs) affect the endocannabinoid system. It aids digestion, inflammatory reactions, pain alleviation, and temperature control. According to Gutiérrez-Ramírez et al. (2017), CBD also inhibits the breakdown of the body's neurotransmitters. The endocannabinoid system will be able to perform better as a result. Also, there is a reduced risk of developing a clinical endocannabinoid deficit.

     The CB1 and CB2 receptors are other points of distinction between CBD and THC. CBD doesn't directly interact with these receptors. Furthermore, the action of the fumarylacetoacetate (FAA) is impeded. FAA is an enzyme that breaks down anandamide. This neurotransmitter regulates sleep, emotional response, memory, hunger, and digestion. Because of CBD's propensity to promote digestion, scientists want to learn more about how one may use CBD oil to treat digestive system ailments in the future.

    Benefits of Cannabidiol (CBD) on the Gut

    Endocannabinoid receptors spring to mind when thinking about CBD's gut health advantages. Having them around is good for your health because when your stomach is out of whack, it affects every part of your body. Dysbiosis has a cascading impact on your whole body, affecting everything from your immune system to your emotions. CBD may improve your overall health by correcting imbalances in your digestive system. The immune system and inflammation play key roles in the beneficial effects of CBD on gut health.


    Inflammation is likely to be part of any digestive issues you may be experiencing. Inflammation in any region of the digestive system may cause various symptoms. A lack of nutritional absorption may cause malnutrition. Dehydration and exhaustion are side effects of diarrhea. According to Atalay et al. (2020), CBD alleviates inflammation in the body. For instance, CBD reduces the capsaicin receptor's sensitivity in the stomach. This receptor causes mucous membrane inflammation. This compound causes the burning feeling many individuals feel after eating spicy meals.

    Immune System Response

    Immune function is enhanced as a result of the anti-inflammatory properties of CBD. Research suggests a strong connection between gut bacteria and the immune system. A dysbiotic stomach may cause your immune system to overreact, leading to inflammation. CBD reduces an overactive immunological response. Therefore, a healthier immune system can easily handle environmental pollutants and allergies.


    CBD is highly beneficial for your digestive system. It aids digestion and, as a result, enhances nutritional absorption. It also strengthens the intestinal barrier and helps prevent or treat gastrointestinal diseases like leaky gut. CBD also boosts the immune system and lowers inflammation.

    CBD is an anti-anxiety agent because it helps to maintain healthy microbiota. It has been shown to lessen the symptoms of AFS by lowering stress levels.

    CBD interacts with the endocannabinoid system and strengthens the function of anandamide. This neurotransmitter regulates mood, sleep, and digestion. Additionally, CBD properly balances your digestive system.



    Rowland, I., Gibson, G., Heinken, A., Scott, K., Swann, J., Thiele, I., & Tuohy, K. (2018). Gut microbiota functions: metabolism of nutrients and other food components. European journal of nutrition, 57(1), 1-24.

    Marcon, A. R., Turvey, S., & Caulfield, T. (2021). 'Gut health'and the microbiome in the popular press: a content analysis. BMJ open, 11(7), e052446.

    Clarke, G., Stilling, R. M., Kennedy, P. J., Stanton, C., Cryan, J. F., & Dinan, T. G. (2014). Minireview: gut microbiota: the neglected endocrine organ. Molecular endocrinology, 28(8), 1221-1238.

    Campos, A. C., Moreira, F. A., Gomes, F. V., Del Bel, E. A., & Guimaraes, F. S. (2012). Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Philosophical Transactions of the Royal Society B: Biological Sciences, 367(1607), 3364-3378.

    Jadoon, K. A., Tan, G. D., & O'Sullivan, S. E. (2017). A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study. JCI insight, 2(12).

    Gutiérrez-Ramírez, J. M., Flores-González, L. A., Toledo-Vázquez, A., Sánchez-González, L. C., Reyes-Solis, H., & González-Pérez, M. (2017). Quantum Analysis of the Effect of Cannabidiol on Neurotransmitters. World Journal of Pharmaceutical Research, 6(13), 31-38.

    Atalay, S., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2020). Antioxidative and anti-inflammatory properties of cannabidiol. Antioxidants, 9(1), 21.

    Nicola Boulton
    Nicola Boulton

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