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  • by Nicola Boulton August 26, 2022 5 min read

    How Pain Impacts the Brain. How Much CBD To Take for pain

    Pain is a complicated and multifaceted phenomenon. Our biology, emotions, social context, and prior experiences all influence our sense of pain. Those who suffer from chronic pain already know what a great weight it is to bear. Herein, the rationale for using CBD to treat pain, the impacts of pain on the brain, and How much CBD to take for pain are highlighted.

    Chronic pain affects not just the body but also the mind of the person experiencing it. Chronic pain sufferers' brains are altered in ways that may partly explain the condition's influence on emotional well-being. Diagnostic and therapeutic practitioners and their patients seek safe and effective alternatives to opioids because of the persistent problems of chronic pain treatment and the implications of the opioid crisis. Some people are interested in utilizing CBD for various medical conditions, including pain, because of the legalization of marijuana in many states and societal acceptance of this medication.

    What Is the Rationale for Using Marijuana To Treat Pain?

    According to Boyaji et al. (2020), while THC has psychoactive effects, CBD has emerged as a viable medicinal agent for pain, seizures, anxiety, and inflammation, without the psychoactive side effects. A growing body of data from animal research shows that CBD exerts its pain-relieving effects via its multiple interactions and regulation of the endocannabinoids, inflammatory, and nociceptive systems. In the human body, there are cannabinoid receptors that interact with our naturally-occurring cannabinoids. Many bodily systems, including metabolism and hunger, mood, pain, anxiety, and pain perception, are controlled by this system.

    Impacts of Pain on the Brain

    Being in pain for an extended time is physically and psychologically unsustainable. Long-term chronic pain may adversely affect a person's mental and physical well-being. Consider the following factors;

    Low Self-Esteem, Worry, and Despair

    According to Mun et al. (2021), chronic pain has a major influence on our mood, one of the most significant consequences on our brains. Aside from physical discomfort, chronic pain may significantly impact our mental well-being and quality of life. Being diagnosed with chronic pain and realizing that this discomfort will not go away immediately might be a tough idea. Medical practitioners and society frequently instill a false understanding of what "chronic" implies because of the stigma attached to the condition and a lack of information. Chronic pain might seem like it has robbed you of all of your happiness. A lack of treatment might lead to a decrease in one's ability to function. Many individuals cannot work or maintain the interests and pastimes they had before from being chronically sick. It may seriously harm a person's state of mind due to this.

    The inability to work brings with it additional financial concerns. Worrying about pain becoming worse might lead to increased stress and worry. People who are socially isolated may believe they are the only ones going through what they are, which may lead to a decline in mood. Chronic pain affects the sufferer and the patient's family members. In times of crisis, family members typically step in to help ease their tensions. It is common for people who are in pain to feel humiliated, guilty, or like a 'burden' when they have to ask for assistance or lose their independence. Patient hypervigilance is typical among chronic pain sufferers unduly preoccupied with their suffering. Catastrophizing is when patients become too concerned with their pain to the point that it starts to interfere with their day-to-day activities. Patients with anxiety about worsening their pain or reinjuring themselves avoid activities out of dread, referred to as "fear avoidance."

    Alterations in the Way the Brain Processes Information

    Neuroplasticity refers to how our brains change from what we experience in our surroundings and lives. According to Simons et al. (2014), brain and central nervous system neuropathways are altered by chronic pain. They become too sensitive to stimuli. The nervous system may undergo structural and functional changes, resulting in pain no longer being a symptom of the original cause but becoming a distinct medical illness in its own right. Hyperalgesia is a term used to describe the sensation of experiencing greater pain than normal in response to acute pain. Allodynia is a condition in which patients feel pain even though they should not, such as when they scrape or wash their skin. One of the most challenging symptoms of fibromyalgia to deal with is the constant aches and pains.

    Changes in the Brain's Structure

    Long-term suffering alters the brain's structure. The gray matter in the brain shrinks as a result of chronic pain. For learning and memory, attention, motor control, and coordination are all controlled by the grey matter in the brain. According to Shelby et al. (2021), chronic pain sufferers may have difficulty remembering new information or acquiring new skills, concentrating on a single job, thinking through difficulties, and finding answers. One might have impaired motor control. As a result, chronic pain sufferers may have difficulty controlling their motor functions, including everyday tasks and motions, in addition to more precise movements and coordination. More grey matter is lost when a person suffers from chronic discomfort. You may re-establish normal brain functioning and cure the effects of chronic pain by receiving good therapy. However, the more gray matter you lose due to chronic pain, the longer you go without treatment. It will take longer to heal if you go without therapy for an extended period.

    How Much CBD to Take for pain

    There isn't a single CBD dose that works for everyone. Cannabidiol's nature is complicated, as are the cannabis plants, and the absorption of CBD may be affected by too many external circumstances. All of these factors, as well as the cannabis spectrum and your weight, influence your product's strength. Ensure to take any general dosage instructions for particular diseases as a point of reference rather than the sole method of administering CBD. Begin with a modest dose and gradually increase it till you get the desired results. CBD's effects on your body might shift over time, so it's important to keep tabs on how you respond to it.


    In light of the bad consequences chronic pain may have on a person's health, it's hard not to be concerned. Try not to become too stressed out. The great majority of these problems have reversible consequences. Losing weight is a possibility. It is possible to return to your pre-injury physical state. It is possible to minimize stress and its effects to a reasonable level. Chronic pain, maybe most significantly, is treatable! CBD may save your life! Before opting for CBD treatment, people with chronic pain should learn more about the condition causing the pain, join a support group, and practice relaxation methods. One-on-one counseling with a mental health expert may also be an option.


    Boyaji, S., Merkow, J., Elman, R. N. M., Kaye, A. D., Yong, R. J., & Urman, R. D. (2020). The Role Of Cannabidiol (CBD) In Chronic Pain Management: An Assessment Of Current Evidence. Current Pain And Headache Reports, 24(2), 1-6.

    Mun, C. J., Campbell, C. M., Mcgill, L. S., & Aaron, R. V. (2021). The Early Impact Of COVID-19 On Chronic Pain: A Cross-Sectional Investigation Of A Large Online Sample Of Individuals With Chronic Pain In The United States, April To May 2020. Pain Medicine, 22(2), 470-480.

    Shelby, T., Hennepin, R., Schenck, C., Clark, K., Meyer, A. J., Goodwin, J., ... & Grau, L. E. (2021). Implementing A Volunteer Contact Tracing Program For COVID-19 In The United States: A Qualitative Focus Group Study. Plus One, 16(5), E0251033.

    Simons, L. E., Elman, I., & Borsook, D. (2014). Psychological Processing In Chronic Pain: A Neural Systems Approach. Neuroscience & Biobehavioral Reviews, 39, 61-78.

    Nicola Boulton
    Nicola Boulton

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