For lion's mane, I find it most effective when taken in the morning. It supports cognitive function and mental clarity, so starting your day with it can help keep your mind sharp throughout. Cordyceps is great to take in the early afternoon, especially if you need an energy boost. It can help improve physical performance and combat fatigue, making it ideal for that mid-day slump. Always follow the dosage recommendations on the supplement packaging and see how your body responds.