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  • by Nicola Boulton December 12, 2023 6 min read

    CBD Capsules Dosage Guide

    The quest to consume cannabidiol has grown significantly in recent years, and more people are embracing this organic chemical product for its myriad benefits. However, it is important to consider the right dosage. This article explores the CBD capsule dosage guide, along with the benefits of CBD and the frequently asked questions about this cannabinoid.

    Most consumers consider CBD a suitable alternative to other inorganic substances to relieve pain and inflammation. CBD improves sleep quality and alleviates stress and anxiety. It's multifaceted since it can be incorporated into various products, such as tinctures, gummies, vapes, and capsules. Capsules don't have a distinct taste. They are ingested orally, and they disguise CBD oil's earthy taste. Several factors influence the right CBD capsule dosage to consume, including your metabolism, age, weight, and tolerance to cannabidiol. Although overdosing on CBD isn't entirely possible, overconsumption of CBD capsules may cause a few side effects. It is also important to find out if you have allergies to CBD capsules since it may interfere with your tolerance to CBD.

    What Are CBD Capsules?

    CBD capsules have a gelatin outer casing and are infused with a precise amount of CBD oil. CBD is an organic chemical compound obtained from hemp. It is popular due to its non-psychoactive benefits; thus, it does not cause a 'high' sensation when consumed. It is imperative to distinguish that hemp and marijuana are plant strains of the cannabis plant, but they have varying effects and chemical components. For example, marijuana has higher levels of THC (tetrahydrocannabinol), an organic chemical compound with euphoric effects that temporarily alter the user's mental state. In contrast, hemp has higher levels of CBD, which is non-psychoactive and has several therapeutic benefits.

    CBD capsules contain other essential chemical compounds, such as terpenes and flavonoids. Terpenes are organic chemical compounds found in plants and are responsible for their distinct scent. Cox-Georgian et al. (2019) observed that they have anti-inflammatory properties that alleviate muscle and skin inflammation. Moreover, flavonoids alleviate oxidative stress in the muscles and tissues.

    CBD Capsules Dosage Guide

    CBD capsules are available in several potencies. Some capsules contain 10mg of CBD oil, while others contain as much as 50mg of CBD oil. While using higher potency CBD capsules, you'll only need to consume fewer capsules. It is necessary to consult your doctors concerning the right dosage since they can examine any possible allergies and your tolerance to cannabidiol. The following are variables that determine how many CBD capsules you should consume:

    The Health Condition Being Addressed

    Moltke & Hindocha (2021) suggested that CBD has several therapeutic effects, such as pain relief, reduced anxiety, and improved sleep quality. The condition being addressed would determine the amount of CBD capsules to be taken. To improve sleep quality and reduce insomnia, consume 10-25 mg CBD capsules. For anxiety relief, 20-30mg of CBD would be effective.

    CBD capsules can also improve your concentration, and consuming 10-20mg of CBD is advisable for an almost guaranteed efficacy. While alleviating pain and inflammation, 10-50 mg of CBD capsules may be effective, depending on the type and intensity of pain.

    Metabolism

    Your metabolism also determines the right amount of CBD edibles to consume. If you are an active person, you may need to consume more CBD capsules since your body breaks down compounds faster.

    In addition, the effects of CBD capsules are experienced faster when the capsules are consumed on an empty stomach. Consuming CBD capsules after a meal would reduce its metabolism but increase its bioavailability since more cannabidiol reaches the bloodstream.

    Bioavailability

    Bioavailability refers to the amount of CBD absorbed into the bloodstream. Various CBD consumption methods have different bioavailabilities. For example, CBD tinctures and vapes have a higher bioavailability since they do not have to be gut processed. Therefore, they don't have to undergo first-pass metabolism in the liver and are absorbed into the bloodstream almost directly.

    However, oral CBD consumption methods, such as capsules, have a slower bioavailability since they have to be gut processed before being absorbed into the bloodstream. However, their effects can last for 3-6 hours in the body, making the more effective.

    Body Weight

    Your body weight determines how quickly your body breaks down various compounds. People with a lower weight would require lesser CBD capsules than people with a higher weight.

    CBD is a fat-soluble compound and can be stored under the fat tissues after being absorbed into the bloodstream. Therefore, people with a higher weight would need more CBD capsules to experience its therapeutic effects fully.

    Type of CBD Capsules

    CBD capsules are available in several spectra, including full spectrum, CBD isolate, and broad-spectrum CBD capsules

    Full-spectrum CBD capsules contain several cannabinoids and chemical compounds, including terpenes, flavonoids, CBD, THC, and CBC (cannabichromene). However, the levels of THC are relatively lower to prevent any psychoactive effects.

    Broad-spectrum CBD capsules are similar to full-spectrum CBD capsules. However, they do not contain THC since it is removed after the initial extraction process.

    CBD isolate capsules are considered the purest since they only contain cannabidiol as the primary chemical compound.  

    Full-spectrum and broad-spectrum CBD capsules exhibit the entourage effect. They have similar chemical compounds that work harmoniously to enhance CBD's therapeutic effects. Therefore, it is easier to determine the right dosage of CBD to consume while using full-spectrum or broad-spectrum CBD capsules.

    Frequently Asked Questions about CBD Capsules

    What Are the Benefits of CBD Capsules?

    • Grimison et al. (2020) stated that CBD capsules have anti-emetic properties that improve gastrointestinal health.
    • Jastrząb et al. (2021) suggested that CBD capsules have anti-inflammatory properties that alleviate muscle aches and inflammation.
    • According to Dawidowicz et al. (2021), CBD has antioxidant properties that reduce oxidative stress in the muscles and tissues.
    • Khalsa et al. (2021) stated that CBD capsules have anti-anxiety properties that alleviate higher stress and anxiety levels.
    • Hindelang et al. (2022) observed that CBD might reduce high blood pressure and improve heart health by improving sleep quality.

    How Do CBD Capsules Work?

    The CBD extract interacts with the endocannabinoid system after the capsules have undergone first-pass metabolism. The endocannabinoid system is a complex system that regulates various body functions like digestion, sleep, and metabolism, ensuring they remain in a homeostatic state. It comprises receptors such as CB1 and CB2, enzymes, and endocannabinoids such as anandamide. CBD binds indirectly with CB2 receptors, which are abundant in the peripheral nervous system, alleviating pain and inflammation by transmitting signals to pain receptors in the body. CBD also improves sleep quality by enhancing anandamide's function and triggering increased serotonin production.

    Do CBD Capsules Have Any Side Effects?
    CBD capsules may cause fatigue and changes in weight and appetite. It is necessary to consume the right dosage and purchase higher-quality CBD capsules.

    Conclusion

    CBD capsules are pill-like substances that contain a precise amount of CBD oil. The capsules must be gut processed before they are absorbed into the bloodstream. In addition, several factors determine the right CBD capsule dosage to consume.

    People with a higher body weight would require more CBD capsules than those with a lower body weight. In addition, consuming CBD capsules on an empty stomach would increase its metabolism while reducing its bioavailability. If you are physically active, you may need more CBD capsules since the body metabolizes the capsules quicker.

    CBD capsules are popular for their anti-emetic, antioxidant and anti-inflammatory properties. However, purchasing higher-quality CBD capsules is important to minimize the possible side effects.

    References

    Cox-Georgian, D., Ramadoss, N., Dona, C., & Basu, C. (2019). Therapeutic and medicinal uses of terpenes. In Medicinal Plants (pp. 333-359). Springer, Cham.

    Jastrząb, A., Jarocka-Karpowicz, I., Markowska, A., Wroński, A., Gęgotek, A., & Skrzydlewska, E. (2021). Antioxidant and anti-inflammatory effect of cannabidiol contributes to the decreased lipid peroxidation of keratinocytes of rat skin exposed to UV radiation. Oxidative Medicine and Cellular Longevity2021.

    Dawidowicz, A. L., Olszowy-Tomczyk, M., & Typek, R. (2021). CBG, CBD, Δ9-THC, CBN, CBGA, CBDA and Δ9-THCA as antioxidant agents and their intervention abilities in antioxidant action. Fitoterapia152, 104915.

    Khalsa, J. H., Bunt, G., Maggirwar, S. B., & Kottilil, S. (2021). COVID-19 and cannabidiol (CBD). Journal of Addiction Medicine15(5), 355.

    Hindelang, P., Scharinger, A., Richling, E., Walch, S. G., & Lachenmeier, D. W. (2022). Using the BMD approach to derive acceptable daily intakes of cannabidiol (CBD) and tetrahydrocannabinol (THC) relevant to electronic cigarette liquids. Frontiers in Bioscience-Landmark27(8), 228

    Moltke, J., & Hindocha, C. (2021). Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems. Journal of cannabis research3(1), 1-12.

    Nicola Boulton
    Nicola Boulton


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