Curcumin is the active ingredient in turmeric, and it has drawn attention from the medical and scientific sectors because of its role in the treatment of inflammatory and oxidative diseases. This supplement lessens inflammation and muscle pain after exercise, and athletic and active people can benefit from it.
Research has shown that turmeric offers considerable health benefits for the body and brain. Many of these health benefits are brought on by curcumin, the main bioactive ingredient in this spice. It should be taken in small doses if prescribed as a medical diagnosis. Most of its advantages are due to its antioxidant and anti-inflammatory qualities.
What Is Curcumin
Curcumin is a spice found in turmeric; it has a mustard hue. Joseph et al. (2018) showed that cuisines that use turmeric benefit greatly from its anti-inflammatory properties and golden hue. It is an ideal spice to include in your diet because of the multiple health benefits it provides. In the Curcuma longa plant (a member of the ginger genus), the root is where turmeric is harvested for its medicinal properties. Curcumin, turmeric's active component, gives the spice its distinctive yellow color. Despite its well-known antioxidant and anti-inflammatory effects, Ebrahimzadeh et al. (2021) reported that curcumin is being investigated as a possible treatment for inflammatory disorders like arthritis and ulcerative colitis.
The Benefits of Curcumin
The Anti-Inflammatory Properties of Curcumin
The anti-inflammatory properties cannot be overstated, they aid in the fight against foreign invaders and the repair of the body. The short-term benefits of acute inflammation outweigh the risks of long-term, tissue-damaging inflammation. Furman et al. (2019) suggested that chronic inflammation, even at low levels, may have a role in a range of health problems and diseases. To name a few: coronary artery disease, some types of cancer, diabetes, obesity, and Alzheimer's disease. The prevention and treatment of these diseases can benefit greatly from any measure that lowers chronic inflammation. Yallapu et al. (2015) stated that although inflammation is a complex condition, curcumin is a bioactive molecule that can be used to reduce inflammation.
Enhancing the Body's Antioxidant Power
Liguori et al. (2018) found that many diseases, including aging, are thought to be caused in part by oxidative damage. As a result, potent oxidizing molecules with unpaired electrons, known as free radicals, are produced. Fats, proteins, and DNA are some organic molecules that free radicals react with. Antioxidants shield the body from the damaging effects of free radicals. According to Nimse & Pal (2015), the molecular composition of curcumin makes it a powerful antioxidant capable of neutralizing free radicals. According to Asouri et al. (2013), curcumin inhibits the activity of free radicals and boosts the activity of other antioxidants.
It Improves Heart Health
Nowbar et al. (2019) explained that coronary heart disease is one of the top causes of death worldwide. There are many different variables that might lead to heart disease; however, did you know that Curcumin can stop or reverse many steps in the development of heart disease? According to Saeidinia et al. (2018), Curcumin's most significant benefit in the fight against heart disease may be the increased endothelial function. Turmeric has been shown to help lower blood pressure and cholesterol levels, two issues that coexist. The use of turmeric can improve general heart health, reduce the risk of heart diseases, and even prevent heart attacks. This is due to curcumin’s ability to reduce cholesterol and blood pressure. Saeidinia et al. (2018) stated that people using blood pressure medication should speak to their doctor about the potential risk of bleeding before starting a turmeric regimen. Monitor the blood pressure and cholesterol levels closely by getting regular blood tests.
For a long time, scientists assumed that neurons couldn't split or multiply because their structure wasn't fully understood. However, Neurons can make new connections, and multiply in specific sections of the brain. Brain-derived neurotrophic factor (BDNF) plays an important role in this process. This protein is found in areas of the brain associated with food, drink, and body weight. BDNF protein levels have been linked to a variety of mental diseases, including depression and Alzheimer's disease. Han et al. (2021) explained that curcumin boosts BDNF levels, thus it could delay or even reverse many brain disorders and decline in brain function due to old age. Although these experiments were conducted on animals, it's impossible to predict what the outcomes signify for humans. Because it affects BDNF levels, it makes sense that it would also help with memory and concentration.
May Prevent Cancer
Uncontrolled cell growth is a frequent cause of cancer. Taking curcumin supplements appears to have a positive effect on a variety of malignancies. Das et al. (2020) noted that Curcumin has been intensively researched as a cancer-fighting herb, and it has been discovered to influence cancer growth and development . Cancerous cells may be eliminated, new tumor vasculature may be prevented, and disease dissemination may be slowed. Human experiments with high-dose curcumin are still in the works. This approach may help to prevent cancers like colorectal cancer and those of the digestive tract, like precancerous cells.
To maximize the benefits of turmeric, consume it whole rather than adding it to dishes. A dietary supplement is likely to be required to have any effect. The amount of turmeric or curcumin a person should consume daily depends on the ailment they are treating as well as their genetic makeup. Between 0.5 to 3 grams of turmeric or curcumin should be consumed on a daily basis. Before frequently taking turmeric supplements, seek medical advice to be safe.
Asouri, M., Ataee, R., Ahmadi, A. A., Amini, A., & Moshaei, M. R. (2013). Antioxidant and free radical scavenging activities of curcumin. Asian J. Chem, 25(13), 7593-7595.
Das, S., Dey, A., Das, S., & Nandy, P. (2020). An Overview on Cancer-Fighting Phytochemicals from Selected Medicinal Plants in Bengal. Mathews Journal of Pharmaceutical Science, 4(2), 1-16.
Ebrahimzadeh, A., Abbasi, F., Ebrahimzadeh, A., Jibril, A. T., & Milajerdi, A. (2021). Effects of curcumin supplementation on inflammatory biomarkers in patients with rheumatoid arthritis and ulcerative colitis: a systematic review and meta-analysis. Complementary Therapies in Medicine, 61, 102773.
Furman, D., Campisi, J., Verdin, E., Carrera-Bastos, P., Targ, S., Franceschi, C., ... & Slavich, G. M. (2019). Chronic inflammation in the etiology of disease across the life span. Nature medicine, 25(12), 1822-1832.
Han, Y., Chen, R., Lin, Q., Liu, Y., Ge, W., Cao, H., & Li, J. (2021). Curcumin improves memory deficits by inhibiting HMGB1‐RAGE/TLR4‐NF‐κB signalling pathway in APPswe/PS1dE9 transgenic mice hippocampus. Journal of Cellular and Molecular Medicine, 25(18), 8947-8956.
Liguori, I., Russo, G., Curcio, F., Bulli, G., Aran, L., Della-Morte, D., ... & Abete, P. (2018). Oxidative stress, aging, and diseases. Clinical interventions in aging, 13, 757.
Nimse, S. B., & Pal, D. (2015). Free radicals, natural antioxidants, and their reaction mechanisms. RSC advances, 5(35), 27986-28006.
Nm, J., Joseph, A., Maliakel, B., & Im, K. (2018). Dietary addition of a standardized extract of turmeric (TurmaFEEDTM) improves growth performance and carcass quality of broilers. Journal of animal science and technology, 60(1), 1-9.
Nowbar, A. N., Gitto, M., Howard, J. P., Francis, D. P., & Al-Lamee, R. (2019). Mortality from ischemic heart disease: Analysis of data from the World Health Organization and coronary artery disease risk factors From NCD Risk Factor Collaboration. Circulation: cardiovascular quality and outcomes, 12(6), e005375.
Saeidinia, A., Keihanian, F., Butler, A. E., Bagheri, R. K., Atkin, S. L., & Sahebkar, A. (2018). Curcumin in heart failure: a choice for complementary therapy?. Pharmacological Research, 131, 112-119.
Yallapu, M. M., Nagesh, P. K. B., Jaggi, M., & Chauhan, S. C. (2015). Therapeutic applications of curcumin nanoformulations. The AAPS journal, 17(6), 1341-1356.
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