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  • by Nicola Boulton August 30, 2022 5 min read

    Are You Aware Of These Interesting Facts About CBD?

    CBD topicals are slowly gaining acceptance with the majority of the masses due to their effectiveness in localized pain relief applications. However, it would be great to understand their work before using one of these products. This article gives you an insight into how topicals work in the body.

    CBD and THC are the two most prevalent and well-known cannabinoids from hemp. The two cannabinoids comprise at least forty percent of the hemp's cannabinoid profile. The rest is occupied by other cannabinoids such as CBN, CBDV, and CBG. In addition, other compounds such as terpenes and flavonoids boost the efficacy of CBD. After extraction from hemp, the oils are made into different products such as topicals, tinctures, and vapes used in different administration methods. These articles will elaborate on how topicals work with the body, their efficacy, and the number of dosages used when using topical CBD.

    Many Powerful Scientific Kinds of Research Always Revolve Around CBD

    Sherer & Schechter (2016) explained that more than eighty-five cannabinoids exist in the plant, referred to as Marijuana, from which THC and CBD are the most acknowledged. The Medical research and clinical trials which have been carried out have shown the effectiveness and the adverse effects of using CBD.

    CBD Cannot Intoxicate an Individual

    Unlike THC, CBD does not possess a hallucinogenic character that gets one stoned because of using it. Mechoulam & Parker (2013) explained that THC attaches itself to an individual's CB1 and CB2 sensory receptors, resulting in intoxicating and bodily excitements. Still, CBD does not bind itself to CB1 and CB2 sensory receptors. The binding-free characteristic of CBD makes it fit for use by anybody, including individuals whose occupations need sound judgments.

    CBD Possesses Curative Properties

    Pharmaceutics medication aids in treating health and medical illness worldwide, but the reaction can regularly decline or even exceed the benefits. A situation like this has always made CBD the best. CBD is regarded as non-irritating and almost entirely after-effect free, so for certain individuals, it can stand in for other pharmaceuticals.

    The Law permits the Use of CBD

    CBD is a natural product that can be extracted from industrial hemp plants and purposely grown for medicinal use. The legalization of the use of Marijuana is different depending on the locality of an individual. Ropero-Miller & Stout (2008) explained that CBD is non-regulated due to the THC content that industrial hemp plants incorporate, which is less than 0.03%.

    CBD stimulates CB1 and CB2 sensory organs.

    When CBD is consumed, it takes hold of the significant cannabinoid sensory organs in the body. The CB1 receptor is located in the brain and peripheral nervous system, while CB2 is in the gastrointestinal tract, immune system cells, and peripheral nervous system.

    It is important because the results of activating these sensory organs can be perceptible. Some researchers have discovered that the triggering effect of CB2 on sensory organs can cleanse the brain of beta-amyloid protein, a plaque in people with Alzheimer's. At the same time, activation of CB1 receptors can positively reduce fear, impact depression, reduce paranoia, lower blood pressure, and lower intestinal inflammation. CB1 receptor stimulation can even give relaxation to one of the most widespread mental illnesses in the United States – anxiety.

    CBD Is Effective for Anxiety

    Anxiety is frequently cured through psychotherapy, administration of medication, or both psychotherapy and administration of medication. Oberbarnscheidt & Miller (2020) explained that cannabis and Cannabinoid Research affirmed that over sixty percent of cannabidiol users disclosed consuming CBD to heal a medical state. These users' most widespread conditions were anxiety, pain, and depression.

    Human Beings Naturally Produce Cannabinoids

    Human beings naturally manufacture cannabinoids in our endocannabinoid system – one affecting numerous bodily functions such as appetite, mood, pain, and varying cognitive functions. One of the most important endocannabinoids is anandamide which is the joy particle. Anandamide is considerable because it activates our CB1 sensory organs. These receptors aid in the following:

    • Decrease anxiety, paranoia, and fear
    • Lower blood pressure
    • They are known to stop the proliferation of breast cancer cells.
    • Lower intestinal inflammation
    • Relieving depression
    • Decrease the occurrence of Leaky Gut Syndrome
    • Benefits for people with post-traumatic stress disorder (PTSD)

    While anandamide works to stimulate CB1 sensory organs in the bodies of human beings, it also secretes an enzyme referred to as FAAH that disintegrates down anandamide. Leweke et al. (2012) explained that CBD is important because it hinders FAAH’s capability to do its job. CBD also stimulates PPAR-gamma sensory organs, which play functions of lipid absorption, dopamine release, insulin sensitivity, and the deterioration of beta-amyloid plaque, which can perfectly affect diseases such as schizophrenia, diabetes, and Alzheimer's. 

    CBD affects Clinical Endocannabinoid Deficiency positively (CECD)

    Individuals with CECD manufacture fewer amounts of natural cannabinoids. The adverse results of this reduced production are as follows:  

    • Fibromyalgia
    • Migraines
    • Irritable Bowel Syndrome (IBS)
    • Autism
    • Multiple Sclerosis (M.S.)
    • Post-Traumatic Stress Disorder (PTSD)
    • Parkinson’s Disease Huntington’s Disease

    As expressed before, the pharmaceuticals recommended for these medical conditions can result in side effects more dangerous than the symptoms. It is another section where CBD is seen to be natural and free from side effects, increased manufacturing of cannabinoids in the body to encourage greater health benefits.

    CBD Is Always Safe

    Most human beings generally authorize CBD. It has a fine well-being profile. The U.S. Food and Drug Administration has accepted an oral CBD product, Epidolex, as a therapy for Lennox-Gastaut and Dravet syndromes – two severe childhood-onset seizure disorders.

    CBD Can Naturally Help Those Ailing from Epilepsy and Seizures

    In the identified protection profile of Epidiolex, the DEA has regrouped the drug from Schedule I, which states that there is no medical use for substances like heroin, to Schedule V, which is a low potential for misuse, for example, cough medicine.


    CBD oil is so important as it solves some health issues, such as offsetting anxiety and depression. Studies show that CBD oil effectively treats chronic, non-cancer pain and protects against neurological disease. CBD oil has antioxidant and anti-inflammatory properties and Inhibits arthritis symptoms. In addition, Arthritis involves the deterioration of the tissues in and around the joints.


    Leweke, F. M., Piomelli, D., Pahlisch, F., Muhl, D., Gerth, C. W., Hoyer, C., ... & Koethe, D. (2012). Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Translational psychiatry, 2(3), e94-e94.

    Mechoulam, R., & Parker, L. A. (2013). The endocannabinoid system and the brain. Annu rev Psychol, 64(1), 21-47.

    Oberbarnscheidt, T., & Miller, N. S. (2020). The impact of cannabidiol on psychiatric and medical conditions. Journal of clinical medicine research, 12(7), 393.

    Ropero-Miller, J. D., & Stout, P. R. (2008). Development and production of reference materials for control and calibration of hair drug testing final report. Washington, DC: National Institute of Justice, 224523.


    Nicola Boulton
    Nicola Boulton

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