Is CBG Good For IBS?

Are you struggling with irritable bowel syndrome? Have you heard that CBG can help one heal the condition but are unsure about it? This article explains CBD, its sound, and the types of irritable bowel syndrome, among other aspects.

CBG and cannabigerol have been proven to have potent anti-inflammatory properties. Inflammatory bowel syndrome is mainly caused by chronic inflammation in the bowel. The anti-inflammatory properties of CBG help mitigate the effects of irritable bowel syndrome. It achieves these effects by reducing nitric acid production, augmenting anti-stress defenses, reducing the production of reactive oxygen species, increasing anti-inflammatory cytokines, and fighting oxidative stress. The results of CBG and CBD in an inflammatory compound in the body are similar, additive, or different. It is caused by the different affinity between the two mixtures and the nature of the attachment to the receptors. It is seen that formulating CBG and CBD in a ratio of 3:1 makes it efficient for treating inflammation.

What Is Irritable Bowel Syndrome?

Young (2015) explained that irritable bowel syndrome is a disorder that primarily affects the colon. People are having this health condition experience severe pain in the abdomen. Other symptoms associated with this condition include diarrhea, bloating, and constipation. The state doesn't cause colon cancer or damage the digestive system tract. This gastrointestinal disorder occurs due to a lack of cooperation between the brain and the gut. It leads to increased sensitivity in the intestines, particularly the colon. It also changes how the gastrointestinal muscles contract, thus resulting in pain, diarrhea, and constipation.

Types Of Irritable Bowel Syndrome

Irritable bowel syndrome has been characterized depending on the bowel movement caused. The type of bowel movement will determine the kind of treatment because there are different medications for a specific direction. The following are the common types of irritable bowel syndrome.

• Irritable bowel syndrome with constipation where waste product is lumpy and hard
• Irritable bowel syndrome with diarrhea where poop is loose and watery
• Irritable bowel syndrome has mixed characteristics where the victim simultaneously experiences constipation and diarrhea.

How Does Irritable Bowel Syndrome Affect the Body

If one has irritable bowel syndrome, the large intestines muscles contract more than in healthy people. Frequent contrition causes pain, cramps, and discomfort. Most people with this health condition feature low pain tolerance. People with irritable bowel syndrome have excess bacteria in the gastrointestinal tract, thus leading to its severe symptoms.

What Are the Risks of Developing Irritable Bowel Syndrome

These gastrointestinal infections mainly affect teens to people in their early forties. However, ladies are vulnerable to attack compared to men. The condition may easily target you if:

• One has suffered physical or sexual abuse before
• Conditions on the digestive tract
• Inheritance from family
• Mental state disorders such as stress, anxiety, and depression
• Food tolerance.

What Is CBG And Its Relation to Treating IBS?

Cannabis and its various compounds have a solid history for human medicinal purposes. Its cultivation started when it was used for its fiber to create ropes and clothes. As studies and discoveries are made, more compounds and uses of cannabinoids have been revealed. One of these compounds is CBG, which has several therapeutic benefits. This compound is believed to have the ability to cure irritable bowel syndrome.

Wang et al. (2019) explained that a person who takes CBG does not undergo digestion like other substances. After it is absorbed into the bloodstream, it travels to the endocannabinoid system in the brain. The endocannabinoid system controls all the essential body processes and ensures it works under optimum conditions. The endocannabinoid system features two receptors, i.e., the CB1 and CB2 receptors. The CB1 receptor is found in the central nervous system, whiles the CB2 receptor is located in the peripheral nervous system. When one takes CBG, it binds to these receptors, therefore, bringing with it different effects.

CBG and Irritable Bowel Syndrome

Today, the research done on the potential benefits and effects of CBG is minimal. Due to the scarcity of CBG in hemp, extracting large amounts for studies is not easy. Rein (2020) stated that the current studies reveal that taking CBG interacts with the endocannabinoid system like other cannabinoids such as THC and CBD. However, CBG does not have to store binding properties to the receptors like THC and CBD. Binding with the CB1 and CB2 receptors hinders the reuptake of the anandamide – a cannabinoid naturally produced by the body. Reducing the reuptake of this compound in the system increases its abundance in the blood. A lot of anandamide means the body will have enough to work optimally. Studies reveal that CBG features strong antioxidant properties. This trait makes a better compound for reducing intramolecular pressure, which is effective for glaucoma victims. The endocannabinoid system is crucial in maintaining the digestive system, and so are inflammatory diseases such as irritable bowel syndrome. Although the study about CBG and its effects is still in the infancy stage, scientists hope that further analysis will support it for people suffering from irritable bowel syndrome.

Benefit of CBG for Digestion

Summer-Bayraktar et al. (2016) explained that CBG also features many benefits for the digestive system before its ability to curb irritable bowel syndrome. Studies reveal that CBG can be used to relieve and prevent the occurrence of intestinal inflammation. Inflammation can be caused by several factors, such as over-sensitive immune responses to the digestive system. CBG helps reduce such inflammation, thus ensuring the intestinal lining is not damaged due to inflammation.

Conclusion

The anti-inflammatory properties of CBG help mitigate the effects of irritable bowel syndrome. It achieves these effects by reducing nitric acid production, augmenting anti-stress defenses, reducing the production of reactive oxygen species, increasing anti-inflammatory cytokines, and fighting oxidative stress. The results of CBG and CBD on an inflammatory compound in the body are similar, additive, or different. It is caused by the different affinity between the two mixtures and the nature of the attachment to the receptors. According to research, formulating CBG and CBD in a ratio of 3:1 makes it efficient for treating inflammation.

References

Rein, J. L. (2020). The nephrologist's guide to cannabis and cannabinoids. Current Opinion in Nephrology and Hypertension, 29(2), 248.

Sumer-Bayraktar, Z., Grant, O. C., Venkatakrishnan, V., Woods, R. J., Packer, N. H., & Thaysen-Andersen, M. (2016). Asn347 glycosylation of corticosteroid-binding globulin fine-tunes the host immune response by modulating proteolysis by Pseudomonas aeruginosa and neutrophil elastase. Journal of Biological Chemistry, 291(34), 17727-17742.

Wang, H., Braun, C., Murphy, E. F., & Enck, P. (2019). Bifidobacterium long 1714™ strain modulates brain activity of healthy volunteers during social stress. The American journal of gastroenterology, 114(7), 1152.

Young, G. P. (2015). Molecular tests in stool and blood for colorectal cancer. Pathology, 47, S15-S16.