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  • by Nicola Boulton September 16, 2022 5 min read

    What Is CBG Compared to CBD?

    CBG and CBD are among the common cannabinoids derived from the cannabis plant. For example, they do not have a psychoactive effect. Furthermore, they are essential in the human body since they can relieve pain, reduce inflammation, manage cancer by preventing the growth of cancer cells and prevent and treat bacterial infection. This article explains more about CBG concerning CBD.

    Cannabinoids have garnered more appreciation since they have proved reliable for relieving different health conditions. Initially, cannabis was illegal in many states since it was considered intoxicating. However, the notion has changed since the compounds derived from the plant have several medical and therapeutic effects on the body. People take cannabinoids for different reasons, including relieving pain and reducing anxiety. However, cannabinoids extracted from hemp are legalized since the plant has more cannabidiol than marijuana. However, there are states which legalize the use of marijuana and its compounds. Read on to discover more about CBG about CBD.

    CBG and CBD

    CBG and CBD are all cannabinoids derived from the cannabis plant. They have similar properties, although there are lower CBG concentrations than CBD concentrations. However, there are some steps taken to increase the production of CBG. For example, cross-breeding, genetic mutilation, and development of the CBG strains such as White CBG, Glue CBG, and Jack Frost CBG are considered to have more CBG than others. The main reason for the involvement is to increase the production of CBG.

    CBG, CBD, and THC are the main cannabinoids. According to Watt & Karl (2017), THC is the most popular marijuana compound known for its psychoactive effect; it causes a high feeling.

    Cannabidiol, commonly known as CBD, is widely appreciated for the health benefits it offers the body. Hemp-derived CBD is legal in almost all states. The Food and Drug Administration also emphasizes it since it is safe for human consumption and contains a limited amount of THC. The legal THC amount is below 0.3%, proving not intoxicating. CBD and CBG can be found in the same extract, for example, the broad-spectrum CBD, which contains terpenes, flavonoids, and various cannabinoids. Therefore, CBG is expensive and rare, so you can still benefit from the compound using broad-spectrum CBD.

    CBGA is the acidic form of CBG, and the younger cannabis plants contain more CBG than the fully grown ones. This is because the CBGA is converted to CBD and THC, which is the reason for higher amounts of the two cannabinoids compared to CBG.

    How CBD and CBG Work

    The human body contains an endocannabinoid system in the skin, brain, and nerves. Cannabinoids from the cannabis plant contain the same molecular structure as the cannabinoid receptors. The receptors are divided into two, namely CB1 and CB2. CBD and CBG bind to the CB1 and CB2 receptors to provide relief in the body, while THC acts on the CB1 receptors alone and thus resulting in mental alteration.

    CBD and CBG can be administered into the body by oral ingestion and topical administration. The bests form of cannabinoid use for pain is topicals since they can be applied directly to the affected area providing faster relief from pain.

    Similarities Between CBD and CBG

    CBD and CBG function similarly because they are derived from the cannabis plant. These are all a result of the conversion of CBGA to CBG, CBD, and THC. CBG and CBD interact with the endocannabinoid by binding the CB1 and CB2 receptors. They do not alter the mental state of the user. However, research shows that CBD and CBG can reduce the psychotropic effect of THC.


    According to Pellati et al. (2018), CBG and CBD can help reduce inflammation due to their internal and external anti-inflammatory properties. For example, CBG and CBD can help treat inflammatory bowel disease, a health condition causing severe swelling in the bowel. This condition does not have a cure; however, research shows that inflammatory bowel disease can improve and ease the condition by administering cannabinoids. Also, they can be used on the skin surface and thus reduce skin swelling, thus essential for interacting with acne, psoriasis, and eczema.

    Improve Sleep

    According to Teitelbaum (2019) , cannabinoids (CBD and CBG) can help improve sleep and prevent insomnia since it has a soothing and relaxing effect on the body and the mind. The cannabinoids used for sleep issues target the root cause of the sleep problem. There are many causes of poor sleep; some are the result of diverse health conditions, and others are caused by lifestyle. Blue light gadgets can affect your sleep pattern. Therefore, scientists suggested avoiding blue light for at least four hours before heading to bed since it interrupts melatonin in the brain. Melatonin is responsible for alerting the brain to fall asleep at night, while the circadian rhythm is key in the sleep and awake cycle. Similarly, various health conditions, such as stress and anxiety, can negatively impact sleep.

    Pain Relief

    According to Überall (2020), cannabinoids (CBG and CBD) can naturally ease muscle pain, joints, and nerve. Pain relief is among the main reason for the wide use of cannabinoids. CBD and CBG have a soothing and relaxing effect on the body and the brain.

    Many over-the-counter painkillers and drugs, such as opioids, ease the pain. Opioids are addictive, and many athletes tend to use the drugs to ease sciatic nerve pain caused by the shift of the disc settling on the nerve. CBG is an organic alternative with minimal side effects.

    Antibacterial Effect

    According to Gildea et al. (2022), CBG and CBD can prevent and treat different bacterial infections, including bacteria that cause staph infection. This bacterium is drug-resistant. However, studies show that the administration of CBG can treat the infection. Similarly, when used topically, it can help treat skin infections, including eczema and psoriasis. Learn more about can cbg cause headaches?


    Cannabis compounds are the labs' new and gold-end specimens since they have diverse health benefits. They are among the common natural remedies to alleviate different health conditions. CBG is a minor cannabinoid since it is found in fewer amounts. However, cannabis growers have tried a new method to increase the scarce compound by cross-breeding, genetic mutilation, and developing different CBG strains. Also, you can benefit from the compound using the broad-spectrum CBD, which contains all the cannabinoids, terpenes, and flavonoids except THC. CBD and CBG have different health benefits, for example, relieving pain and inflammation and removing harmful bacteria from the skin. Learn more about is cbg good for gut health?


    Gildea, L., Ayariga, J. A., Ajayi, O. S., Xu, J., Villafane, R., & Samuel-Foo, M. (2022). Cannabis sativa CBD Extract Shows Promising Antibacterial Activity against Salmonella typhimurium and S. Newington. Molecules, 27(9), 2669.

    Teitelbaum, J. (2019). A hemp oil, CBD, and marijuana primer: powerful pain, insomnia, and anxiety-relieving tools. Altern. Ther. Health Med, 25, 21-23.

    Pellati, F., Borgonetti, V., Brighenti, V., Biagi, M., Benvenuti, S., & Corsi, L. (2018). Cannabis sativa L. and nonpsychoactive cannabinoids: their chemistry and role against oxidative stress, inflammation, and cancer. BioMed research international, 2018.

    Überall, M. A. (2020). A review of scientific evidence for THC: CBD oromucosal spray (nabiximols) in chronic pain management. Journal of pain research, 13, 399.

    Watt, G., & Karl, T. (2017). In vivo evidence for therapeutic properties of cannabidiol (CBD) for Alzheimer's disease. Frontiers in pharmacology, 8, 20.

    Nicola Boulton
    Nicola Boulton

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