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  • by Nicola Boulton August 31, 2022 5 min read

    Why is CBD Not Working for You? - Know the Possible Reasons

    Many companies are selling CBD products these days. They are advertised to help with different health conditions. Some people have reported benefiting from CBD, while others do not feel the effects. How do you know that CBD is not working for you? What might be the reason, and what can you do? This article answers these questions.

    CBD is a natural product extracted from the cannabis plant and has amazing benefits for most people. It is available in the market today with companies advertising CBD products as a relief for different conditions. CBD may not be working for others due to some factors. However,  if you buy CBD and find it is not working for you, there might be possible reasons. How can you know whether CBD is working or not? This article looks into CBD's positive and negative effects and why it might not work for some people. Learn more about how to improve your focus?

    What Is CBD

    CBD stands for cannabidiol and is one of the natural components called cannabinoids present in the cannabis plant. The most known cannabinoid is tetrahydrocannabinol and is responsible for the high effect one gets after taking marijuana. CBD is not psychoactive and is mostly present in the hemp plant. CBD is extracted from the plant and used to make products like gummies, tinctures, vapes, creams and balms, and edibles. The type of CBD depends on the extraction method. CBD is grouped in 3. Full-spectrum, Broad spectrum, and isolate CBD. CBD potency also varies in products from low to concentrate. There are

    How to Know CBD is Working

    Alger (2013)  explained that CBD enters the bloodstream and interacts with the body's endocannabinoid system(ECS). This System regulates body heat, controls pain and inflammation, and maintains body balance or hemostasis. CBD works with ECS receptors to enhance its functioning. Tóth et al. (2019) revealed that CBD has anti-inflammatory and antioxidant properties making it beneficial in reducing pain and inflammation. The study above also suggested that  CBD is used to help with anxiety and stress. Some people use CBD mainly to help with migraines and have a calming and relaxing effect. One should note that CBD takes time to have an effect and is also different for each person. Some people report feeling calmness, an improvement in the skin, and less pain after taking CBD for a while. CBD gives people an improved sense of being overall. Some, however, may not experience these effects after using CBD. To others, CBD not working might mean experiencing side effects.

    Side Effects of CBD

    CBD is considered safe to take and a natural way to help with different conditions. However, it might not have the expected effects on some people. Treese (2020) pointed out that side effects of CBD may include drowsiness, gastrointestinal issues, dry mouth, and nausea. These effects can be mild, and one can stop taking CBD or change the dose and type of product.

    Why CBD Might Not Be Working

    Low Quality

    Not all CBD brands are the same. Different manufacturers use different quality cannabis plants as well as methods of extraction. Gibbs et al. (2019) pointed out that some methods of extracting CBD might not remove all impurities. CBD extracted using liquid solvents such as butane and hexane leave residues in the final product plus chlorophyll from the plant. This leads to low-quality products. CBD may not be working for some because it is of low quality.

    Cannabis Tolerance

    Prolonged use might lead to body tolerance to it like any other drug. When one uses cannabis products or CBD for a long, the body may develop a tolerance to it. One can take a break from using any CBD product for a while and then return to it later. Learn more about how does cbd affect my liver?

    Wrong Dosage

    Taking the right product but the wrong dosage of CBD might not work out. Taking a low amount of CBD might not get one of the effects needed while taking too much might cause adverse effects. Taking the right dosage will depend on one endocannabinoid system, overall health, and to some, weight.

    Mixing CBD with Other Medications

    CBD might not work when mixed with other drugs. If one is under medications, it might not be wise to mix them with CBD. One should seek their doctor's counsel before using CBD if under any other medication or treatment.

    Tips To Try When CBD is Not Working

    Change the Method of Administration

    CBD has to get into the bloodstream to start having effects. Different methods of administering CBD can affect how fast it gets into the System and how long the effects will last. Try switching to another method of using CBD to see the change. Try taking CBD oil orally if you are used to mixing it with other things. When using CBD to help with a skin condition, it is advised to apply it topically.

    Adjust the Dosage Amount

    One of the reasons CBD might not be working is the amount of dosage one takes. You can try taking a higher amount to see the effect. New users are advised to start with a small dosage, see how their body will react to CBD, and adjust the dose gradually. However, if you are experiencing side effects, you may try reducing the dosage.

    Try a Higher Potency

    There are different types of CBD strength, from low to high potency. However, if you notice that a low potency is not working for you, it might be time to upgrade to a higher one. Remember to start with small doses.

    Be Patient CBD Takes Time To Effect

    CBD does not have immediate effects. Some may be expecting it to work immediately. One needs to be patient as it takes time for CBD to enter the bloodstream and start having effects.


    Natural CBD is one of the common products used today by most people. CBD has been used to relieve inflammation and pain and help with stress and anxiety. Some people use CBD to deal with insomnia and sleep. CBD products work differently depending on their body's metabolism and the quality of CBD used. It might also mean they have used a lower or higher dose of CBD than their body needed. One can try changing the Method of administering CBD depending on what they want to deal with and the effect needed. Overall, CBD is a good product that has helped many people, and it might not be possible to find the right product the first time.


    Alger, B. E. (2013, November). Getting High On The Endocannabinoid System. In Cerebrum: The Dana Forum On Brain Science (Vol. 2013). Dana Foundation.

    Gibbs, B., Yates, D. A., & Liebling, J. (2019). CBD In The UK. London, UK: Centre For Medicinal Cannabis.

    Tóth, K. F., Ádám, D., Bíró, T., & Oláh, A. (2019). Cannabinoid Signaling In The Skin: Therapeutic Potential Of The "C (Ut) Cannabinoid" System. Molecules, 24(5), 918.

    Treese, N. M. (2020). Pharmacist's Guide To CBD Oil. US Pharm, 45(3), 20-23.

    Nicola Boulton
    Nicola Boulton

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