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  • by Nicola Boulton August 30, 2022 5 min read

    Natural CBD Oil versus Synthetic Alternatives

    It's no doubt that the use of CBD has been on the rise, partially being its innate ability to solve several issues, as seen from anecdotal evidence. This article discusses the difference between natural CBD oil and synthetic ones.

    From the anecdotal evidence, CBD has been since to aid in ailments such as pain relief, reducing anxiety, stress relief, acne, and eczema, among the many ailments it can treat. Due to its ability to treat many ailments, increased demand for the products has been there, which has exceeded supply. This imbalance has prompted manufacturers to seek better alternatives to meet the demand. This has caused the emergence of synthetic CBD alternatives. Learn more about how often should i take cbd oil?

    Natural CBD Oil versus Synthetic Alternatives

    What is CBD?

    CBD is a compound that is found in the hemp plant. It is distinguished from other compounds since it combines with the endocannabinoid system to disseminate its effects. CBD is located on the trichomes of the CBD flower, which is found on the outer surface of the CBD flower plant.

    Natural and Synthetic

    CBD oil is a natural alternative to synthetic cannabinoids, or cannabis plants may be used to extract the active components of synthetic cannabinoids. This article will discuss the meanings of these two phrases and the benefits of using them to describe CBD oil.

    Comparing CBD Oil with Synthetic Alternatives

    By isolating particular cannabinoids from cannabis plants and chemically changing their molecular structure, synthetic cannabinoids are created. The outcome is a more potent molecule with physiological effects comparable to natural cannabinoids.

    Synthetic production of substances is not new; compounds such as THC oil have been synthesized. In the recent past, THC had been synthesized, but the effect had been devastating because it was seen to cause psychosis (Bloomfield et al., 2019). This phenomenon is backed by the study conducted by. Learn more about how quickly does cbd oil work?

    Natural CBD Oil

    Consumers have some time have had a hard time deciding on whether to take natural CBD or synthetic one. Their disparity, coupled with the fact that synthetic CBD has been tainted names, does not have the capabilities it is its natural counterpart. Look at the two types of CBD before grasping what they are. Mayyah et al. (2020) found that the full spectrum can be used to treat anti-inflammation and pain management.

    Natural CBD refers to CBD that is obtained from the hemp plant. The extraction process can be through solvent extraction, non-solvents use, or CO2 extraction. The use of this method is aimed at getting the CBD compound. However, other compounds can also infiltrate the mixture. This is one of the disparities distinguishing natural CBD from a synthetic one.

    Natural CBD oil contains other compounds, such as terpenes which give the plant its characteristic smell. It is responsible for the aroma and flavor that is found in CBD. Though other flavors can be adjusted, this is the primary flavor. Other compounds such as flavonoids, CBC, CBN, CBT, and cannabidiol are present in the CBD oil extract.

    This compound might lack synthetic CBD oil since its primary chemicals are the use of yeast or other infused bacteria. Its composition with other Compounds makes it have the entourage effect. This is a synergetic feeling that is derived after the use of the full spectrum type of CBD.

    What Is Synthetic CBD?

    Synthetic CBD is made in the lab. At the same time, natural CBD is made directly from the hemp plant. It is made from compounds such as limonene, other bacteria, or yeast chemically diffused to obtain CBD. What comes to mind when you hear the phrase "synthetic"? Meternich et al. (2019) discussed that synthetic CBD could be used to treat epilepsy.

    Perhaps a product created by a scientist, lab technician, or something produced in a factory comes to mind. These two instances are both incorrect. The substance that causes cannabinoids to form in marijuana plants is extracted. Then it is transformed into a liquid form to generate synthetic CBD oil from a plant.

    Natural CBD oil and its synthetic substitutes come from the same source, but their physiological effects differ. What distinguishes CBD oils made from plants from those made from chemicals? Both varieties of items have a variety of advantages and disadvantages. Let's take a closer look at them to help you decide when to use them.

    Full, Medium Spectrum, and Isolate

    The different types of compounds distinguish the range of CBD products it contains. For instance, the full CBD spectrum has most of the compounds. Be it terpenes, flavonoids, 0.3% of THC, CBC, CBN, CBT, and other compounds, all found in the Full spectrum of CBD. Combining all these compounds in a single dosage leads to the entourage effect, which is the synergetic feeling only gained after ingestion.

    Medium spectrum, also known as broad-spectrum, this CBD concentrate contains most of the compounds. Its only disparity from the full spectrum is that, unlike its counterpart, it contains most of the elements that are terpenes and flavonoids and lack CBD. This concentration is best for people who want to enjoy the benefits of other compounds but not THC. It is good for people who are into don't want the psychoactive effect t induced by the use of THC in the body.

    THC also has intervening effects on the body, such as causing red eyes, fatigue after use, poor cognitive response, and loss of memory. Natural CBD Oil is the best to use since the compounds found are natural and have not undergone too many chemical processes.


    It is clear that CBD and its intervening products have been on the rise, and with such, there has been an increased demand for them. The supply of natural products cannot be enough to supplement the demand; hence an alternative is best to be used. This is where synthetic CBD comes into play, using lab extract to make the CBD oil.


    Bloomfield, M. A., Hindocha, C., Green, S. F., Wall, M. B., Lees, R., Petrilli, K., ... & Freeman, T. P. (2019). The Neuropsychopharmacology Of Cannabis: A Review Of Human Imaging Studies. Pharmacology & Therapeutics, 195, 132-161.

    Klotz, K. A., Grob, D., Hirsch, M., Metternich, B., Schulze-Bonhage, A., & Jacobs, J. (2019). Efficacy And Tolerance Of Synthetic Cannabidiol For Treatment Of Drug-Resistant Epilepsy. Frontiers In Neurology, 10, 1313.

    Maayah, Z. H., Takahara, S., Ferdaoussi, M., & Dyck, J. R. (2020). The Molecular Mechanisms That Underpin The Biological Benefits Of Full-Spectrum Cannabis Extract In The Treatment Of Neuropathic Pain And Inflammation. Biochimica Et Biophysica Acta (BBA)-Molecular Basis Of Disease, 1866(7), 165771.

    Ubeed, H. M. S. A., Bhuyan, D. J., Alsherbiny, M. A., Basu, A., & Vuong, Q. V. (2022). A Comprehensive Review On The Techniques For Extraction Of Bioactive Compounds From Medicinal Cannabis. Molecules, 27(3).

    Nicola Boulton
    Nicola Boulton

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