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  • by Nicola Boulton September 14, 2022 5 min read

    Can I Take CBG with Other Medicines?

    Cannabinoids tend to react with other medications. Consult your doctor for more information on the side effects of CBG and their reaction to other drugs. Do not substitute your medicine with cannabinoids since they are not proven effective.

    Cannabinoids are widely appreciated in the world today due to the effect they have on the body. For example, pain relief, alleviation of anxiety and stress, improving sleep, preventing of insomnia, and reducing inflammation. Cannabis was subjected to many laws due to its effect on the mind. However, studies show that cannabinoids found in the plant are reliable and can be used as a natural remedy for different health conditions. Among the common cannabinoids known are CBD, CBG, and THC. However, CBG is not approved for use since they do not have the scientific backing of the claim. Therefore, CBG   cannot be taken with other medications since they can react with the drugs and be problematic.

    What is CBG?

    CBG is the third most known cannabinoid derived from the cannabis and hemp plant. CBG is found in small quantities; thus, the compound is expensive and rare. CBG is high in young cannabis plants since they contain more CBGA, which is the acidic form of CBG. The compound continues to reduce as the plants grow since CBGA is converted to THC and CBD, which become fully grown cannabis plants.

    Cannabis growers have ventured into increasing the production of CBG by practicing cross-breeding and genetic mutilations. Different CBG strains are developed mainly to increase the production of CBG. For example, the glue CBG, white CBGH, and jack frost CBG. They are considered to have more CBG compared to other strains.

    Cannabinoids tend to react with other medications. Therefore, it is advisable not to combine any form with other medication. Consider consulting your doctor for more information on the side effects of CBG and their reaction to other drugs. Do not substitute your medicine with cannabinoids since they are not proven to be ridable. Epidiolex is the only CBD drug approved for medical use in use.

    How CBG Works

    CBG is a form of cannabinoid that differs from the form of administration. CBG is mainly used in its oil form. Naturally, CBG is extracted as powder and mixed with a carrier such as coconut and a hemp seed oil. CBG is derived from the plant by the use of chemicals and CO2. According to Rochfort et al. (2020), CO2 is the bests method of cannabinoid extraction since it does not expose the compound to harsh chemicals which will contaminate the compound, reducing the effect and the potency.

    CBG does not have a psychoactive effect on the brain like THC. Watt & Karl (2017) noted that THC is the common marijuana compound mostly known for its effect on the brain; it alters the user's mental state. CBG, like CBD, works by interacting with the cannabinoid receptors in the body. The cannabinoid receptors in the body are believed to be similar to the cannabinoid receptors in the cannabis plant. CBG binds the CB1 and the CB2 receptors and thus does not have a psychoactive effect on the brain.

    People take CBD for different reasons. However, whichever the reason for talking CBG, there is a need to consider the dosage; it is advisable to start slow and low and gradually increase the amount to your desired amount.

    CBG is rare and expensive, but this does not limit you from benefiting from the compound. The broad-spectrum CBD contains all the cannabinoids, excluding THC, which alters the user's mental state. Acing CBD broad spectrum will be the bests from of benefiting for the CBG haw.

    Factors That Affect the Effects of CBG on the Body

    The Potency

    CBG potency is the strength of the compound; this can be affected by the source of CBG and the extraction method. A cannabinoid compound with high potency has a fast effect on the body compared to allow potent one.

    Body Composition

    Body composition is another factor that can determine the effect of the cannabinoid on the body. For example, a slim person tends to feel the effect faster, unlike the plus-sized person, due to the surface area that the compound has to cover for the effects to surface. However, big-bodied people tend to benefit from the compound much longer since the fats store the cannabinoids, including CBG.

    Body Tolerance

    How many cannabinoids the body can tolerate can affect the effectiveness of the compound in the body. People vary in their tolerance rate; if the body can tolerate more CBG, it will have a fast effect compared to a person with low tolerance.

    The Dosage and Concentration

    CBG products come in different concentrations. When you have a high dose of CBG, the effect will be fast and long compared to the person who uses small doses. Similarly, a highly concentrated CBG compound has a high effect. There are many reasons why people today are using cannabinoids in their daily routine

    Antibacterial and Anti-Fungal Effect

    Cannabinoids have many benefits, including anti-bacterial and anti-fungal effects. Aqawi et al. (2021) observed that CBG could fight staph-causing bacteria known as methicillin-resistant Staphylococcus aureus (MRSA). The eubacteria are known to be drug-resistant, but CBG can help with the infection. CBG can be used to prevent and treat different infections due to disease-causing organisms.

    Huntington's disease

    Míčka (2013) found that CBG can help with Huntington's disease. Huntington's disease is characterized by the breakdown of the brain nerve cells. After the administration of CBG, the patients exhibit improvement. CBG can help with the condition since it provides neuroprotection preventing further damage to the brain cells.

    Anti-inflammation

    Cannabinoids are widely appreciated due to their health benefits, including reducing inflammation. Swelling can be internal or external. Hill et al. (2016) revealed that CBG could treat Inflammatory Bowel Disease (IBD), a condition characterized by severe bowel swelling with pain. It is known for having no cure. However, research shows that patients had improved IBD by reducing inflammation and pain

    Conclusion

    CBG, like any other cannabinoid, is widely used due to the health benefits it has to the body, including anti-inflammation, anti-bacterial, and treating Huntington's disease. CBG is scarce, but consumers can benefit from it using the broad spectrum of CBD. Broad spectrum CBD contains different compounds from the plant, including all cannabinoids, terpenes, and flavonoids except THC, which alters the user's mental state. People respond to cannabinoids differently due to the body composition, the potency of the cannabinoid compound, dosage, and concentration. Cannabis growers have advanced new ways of increasing the production of CBG by developing new strains, cross-breeding, and genetic manipulation.

    References

    Aqawi, M., Sionov, R. V., Gallily, R., Friedman, M., & Steinberg, D. (2021). Anti-Bacterial Properties Of Cannabigerol Toward Streptococcus Mutans. Frontiers In Microbiology, 12, 656471.

    Hill, L. A., Bodnar, T. S., Weinberg, J., & Hammond, G. L. (2016). Corticosteroid-Binding Globulin Is A Biomarker Of Inflammation Onset And Severity In Female Rats. The Journal Of Endocrinology, 230(2), 215.

    Míčka, T. (2013). Getting High To Get Well: Scientific Evidence Of Therapeutic Uses Of Cannabinoids And Terpenoids.

    Rochfort, S., Isbel, A., Ezernieks, V., Elkins, A., Vincent, D., Deseo, M. A., & Spangenberg, G. C. (2020). The Utilization Of Design Of Experiments Approaches To Optimize Supercritical Fluid Extraction Of Medicinal Cannabis. Scientific Reports, 10(1), 1-7.

    Watt, G., & Karl, T. (2017). In Vivo Evidence For Therapeutic Properties Of Cannabidiol (CBD) For Alzheimer's Disease. Frontiers In Pharmacology, 8, 20.

    Nicola Boulton
    Nicola Boulton


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