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  • by Nicola Boulton August 29, 2022 5 min read

    CBD Oil for Narcolepsy

    Do you know what narcolepsy is? Here is what you need about narcolepsy and CBD oil; what are narcolepsy, CBD, and sleep? Does CBD help with narcolepsy and cannabidiol dosage guide for narcolepsy?

    Cannabidiol, often known as CBD, can alleviate various symptoms and conditions, ranging from pain and epilepsy to multiple sclerosis. CBD is a chemical molecule derived from the marijuana plant; however, unlike THC, which is also derived from the marijuana plant, it does not cause euphoria. In several studies, researchers have found that CBD can put people at ease and give them a sense of relaxation. Additionally, it can keep people awake and alert at the same time. Below is more about CBD oil and narcolepsy:

    CBD Oil for Narcolepsy

    What is Narcolepsy?

    Dauvilliers et al. (2019) explained that people who suffer from narcolepsy have a neurological condition that disrupts their normal sleep and wake patterns. Napiness is a common symptom of narcolepsy, which causes sufferers to nod off during the day. These bouts of tiredness come at any time of the day. Narcolepsy is a debilitating condition that can last a person's entire life.

     Several symptoms may accompany narcolepsy, including atrophy of the muscles, hallucinations, and sleep paralysis. The most prevalent symptoms are mental cloudiness and memory lapses. The most common symptom is excessive daytime sleepiness. Inability to concentrate, changes in mood, excessive exhaustion, sudden loss of muscle movements, slurred speech, and total body collapse are all symptoms of this condition. Hallucinations, delusions, and sleep paralysis are more advanced symptoms of schizophrenia. Sleep paralysis is the temporary ability to move or talk while waking up or falling asleep. Learn more about does cbd oil help with psoriasis?

    CBD and Sleep

     Hoyos et al. (2020) explained that there are now on the market medications containing CBD that offers relief from sleeplessness with fewer adverse effects than traditional treatments for sleeping disorders. It has been shown to affect the sleep-wake cycle by interacting with receptors in the endocannabinoid system. Take CBD before bed because it reduces anxiety and pain, contributing to a person’s inability to fall asleep.

    Does CBD Help Narcolepsy?

    There is a growing population of individuals struggling with exhaustion. These individuals are increasingly intrigued as to whether or not the consumption of cannabis oil might improve their condition. The symptoms of narcolepsy include significantly more than just severe fatigue.

    According to Thorpy& Dauvilliers (2015), this disorder may also involve sleep paralysis, hallucinations, and a condition known as cataplexy. Additionally, sleep paralysis may occur during episodes of this condition. Bhattarai& Sumerall (2017) added that the most recent condition is a severe form of sleep disturbance that, as a consequence, causes patients to experience a situation in which they feel as though they have lost some or all control over their muscles. This can be brought on by various feelings, including happiness, grief, and laughing. It is possible to detect narcolepsy at a young, such as when a person is a child or a teenager. This disorder has a significant impact on people's lives.

    Unfortunately, narcolepsy does not have a treatment established via scientific research; however, several helpful stimulants can help manage this illness, such as caffeine and CBD. Figueiredo et.al. (2017)  explained that cannabidiol alleviates symptoms associated with various health conditions, including anxiety, depression, Parkinson's disease, Alzheimer's disease, epilepsy, and chronic pain. It works with the receptors in the body's endocannabinoid system responsible for regulating how the body responds to cannabinoids.

    Kaul et al.  (2021) explained that CBD effectively alleviates the symptoms of a wide variety of sleep-related problems, including narcolepsy, sleep apnea, REM behavior, and insomnia. According to Piña & James (2019),  cataplexy is a prevalent symptom of narcolepsy. It causes a momentary cessation of muscle activity and is typically brought on by abrupt emotions such as anger, surprise, etc. Cataplexy is the most obvious sign of narcolepsy. This disorder has been linked to narcolepsy because it can cause normal sleep patterns to become disrupted.

    Páleníček et al. (2017) showed that CBD is an effective treatment that may assist in managing unexpected feelings that can lead to cataplexy. It binds to the receptors that are present in the brain. Sleepiness throughout the day can lead to exhaustion, difficulty falling asleep, or staying asleep the following night. Including CBD oil as part of the routine may help individuals become more alert during the day. Learn more about using cbd oil for ipf

    Cannabidiol Dosage Guide

    CBD does not have an optimal dose or standard for all users; thus, experimentation is essential in determining what will work best for them. 

    Kovalchuk et al. (2020)   showed that CBD could have various effects, each uniquely determined by the individual's body chemistry and factors such as dosage, product, and time of day. CBD's sedative effects may wear off after prolonged use, and the compound is most useful for producing temporary drowsiness. Products such as CBD tinctures and sublingual sprays give instant effects. However, edibles and oils release CBD more slowly, enabling one to sleep for longer periods. It does not have the same psychoactive properties as THC. CBD doses can range from 10 micrograms to 25 milligrams per serving because each individual's physiology is unique. The only way to identify the appropriate dosage is, to begin with the smallest quantity possible, then gradually increase it until it provides the desired effect.


    It is difficult to talk about the benefits of CBD in treating narcolepsy since more study has to be done to verify the effect of CBD on this illness. However, users claim to benefit from using modest amounts of CBD; they are more alert, which might be something that can aid the individual battling narcolepsy. People with this condition need to ensure that they take an adequate amount of CBD to receive all available benefits. Nonetheless, before using CBD, it is best to discuss the use of this substance with a qualified medical professional to reduce the risk of adverse effects and combinations with other medications.


    Bhattarai, J., & Sumerall, S. (2017). Current and future treatment options for narcolepsy: a review. Sleep Science, 10(1), 19.

    Bassetti, C. L., Adamantidis, A., Burdakov, D., Han, F., Gay, S., Kallweit, U., ... & Dauvilliers, Y. (2019). Narcolepsy—clinical spectrum, aetiopathophysiology, diagnosis, and treatment. Nature Reviews Neurology, 15(9), 519-539.

    Cuba, L. D. F., Salum, F. G., Cherubini, K., & Figueiredo, M. A. Z. (2017). Cannabidiol: an alternative therapeutic agent for oral mucositis?. Journal of Clinical Pharmacy and Therapeutics, 42(3), 245-250.


    Hložek, T., Uttl, L., Kadeřábek, L., Balíková, M., Lhotková, E., Horsley, R. R., ... & Páleníček, T. (2017). Pharmacokinetic and behavioural profile of THC, CBD, and THC+ CBD combination after pulmonary, oral, and subcutaneous administration in rats and confirmation of conversion in vivo of CBD to THC. European Neuropsychopharmacology, 27(12), 1223-1237.

    Kaul, M., Zee, P. C., & Sahni, A. S. (2021). Effects of cannabinoids on sleep and their therapeutic potential for sleep disorders. Neurotherapeutics, 18(1), 217-227.

    Piña-Garza, J. E. J., & James, K. C. (2019). Fenichel's Clinical Pediatric Neurology E-Book: A Signs and Symptoms Approach. Elsevier Health Sciences.

    Suraev, A., Grunstein, R. R., Marshall, N. S., D'Rozario, A. L., Gordon, C. J., Bartlett, D. J., ... & Hoyos, C. M. (2020). Protocol: Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) for chronic insomnia disorder (‘CANSLEEP’trial): protocol for a randomised, placebo-controlled, double-blinded, proof-of-concept trial. BMJ Open, 10(5).

    Thorpy, M. J., & Dauvilliers, Y. (2015). Clinical and practical considerations in the pharmacologic management of narcolepsy. Sleep Medicine, 16(1), 9-18.

    Wang, B., Kovalchuk, A., Li, D., Rodriguez-Juarez, R., Ilnytskyy, Y., Kovalchuk, I., & Kovalchuk, O. (2020). In search of preventive strategies: novel high-CBD Cannabis sativa extracts modulate ACE2 expression in COVID-19 gateway tissues. Aging (Albany NY), 12(22), 22425.


    Nicola Boulton
    Nicola Boulton

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