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  • by Nicola Boulton September 28, 2022 5 min read

    How Does CBD Vape Oil Work?

    If you have never heard of vaping CBD, you probably know somebody who has. The article explains how CBD vape oil works by highlighting these headlines; what CBD vape oil is and how to use it.

    CBD is a chemical compound with over 100 minor cannabinoids in the cannabis sativa plant. In the United States, it is majorly extracted from the leaves and flowers of the hemp plant since the plant is the only cannabis strain that is legal under federal law. It contains a high concentration of CBD compounds and a low level of tetrahydrocannabinol ( THC), making it the best plant to manufacture CBD products. THC is another famous cannabinoid to most marijuana users due to its ability to cause a feeling of highness and confusion. It affects how you respond to space and time. CBD, unlike THC, is a non-intoxicating compound with no mind-altering effects but instead makes you feel energetic, relaxed, calm, less anxious, and sleepy. How does CBD vape oil work?

    How Does CBD Vape Oil Work

    What Is CBD Vape Oil?

    Conuel et al. (2020) noted that upon extraction of cannabidiol, it is diluted with an organic carrier oil like coconut oil, MCT, or hemp seed oil to form highly concentrated CBD oil. The oil is mainly used in CBD products such as topical (salve, cream, lotion), edibles, and vape oil. CBD oil is placed under high pressure during extraction, making molecules split further to form soft textured oil for vaping. CBD oil vape is established under cartridges and sold with vaping electronics such as vape pens, pods, and dabbing rings. Since different companies use different extraction techniques, there are three types of vape oil available in vape stores, including:

    • Full-spectrum CBD vape oil- contains all cannabinoids in the cannabis plant, including small traces of THC. It allows you to benefits not only the health properties exhibited by CBD but also the effects of other cannabinoids like CBN and terpenes. Even though the oil should contain less than 0.3% of THC to avoid a feeling of highness, the Food and Drug Administration ( FDA) has not regulated the manufacturing and selling of cannabis products, making it easier for manufacturers to sell CBD vape oil with THC content above the recommended mark.
    • CBD isolate vape oil- is the purest type of vape oil containing 99% of CBD molecules with no contamination from other cannabinoids. It allows you to inhale highly concentrated cannabidiol within a short period. Therefore, it is the best product to tackle chronic conditions such as pain, high pressure, and treating cancer cells.
    • Broad-spectrum CBD vape oil- lies in the middle of the other two types, whereby contains CBD has the dominant compound with minor cannabinoids like terpenes but no traces of THC. It allows enjoying the entourage effects of cannabis without the risk of getting high.

    How to Use CBD Vape Oil

    Before we venture into how CBD vape oil works, you need to know how to use it. He et al. (2017) stated that vaping CBD oil is the fastest method to incorporate CBD vape oil into the system; it involves using an electronic battery device to mimic smoking, whereby the vape oil is heated in the cartridge, transforming it into CBD vapor that you inhale directly it the lungs then absorbed into the bloodstream. It is the fastest method to take CBD since the onset time for the effects of the cannabinoid to kick in is less than 3 minutes. It bypasses the digestion and metabolic processes, and the circulatory system easily transports fined CBD molecules to all parts of the body.

    How Does CBD Vape Oil Work?

    Inhaled CBD vape oil n the system interacts with your body's endocannabinoid system (ECS), comprising two cannabinoid receptors, including CB1 and CB2 receptors. Corroon et al. (2019) explained that ECS is responsible for maintaining internal and external body balances by elevating pain, anxiety, loss of appetite, stress, and inflammation with the help of body cannabinoids like anandamide and 2-AG. Vaped CBD does not bind with the two receptors like THC does but works with them in the following ways:

    CB2 Cannabinoid Receptors

    CB2 is located in all body parts through the immune system. Vaccani et al. (2005) observed that in case of body imbalances, they are activated by 2-arachidonoyglycerol (2-AG), the prominent body cannabinoid responsible for the immune system's normal inflammatory response. When vaping CBD oil, cannabidiol increases the release of 2-AG endocannabinoid, which binds with CB2 receptors to tackle the following functions;

    • It ensures normal inflammatory responses by modulating immune cells to reduce inflammations in detecting body infections. Inflammations occur when the immune system senses a threat causing excessive intracellular activities that damage the body cells and tissues.
    • CBD vape oil is primarily associated with healing capability. It is because the CB2 bond with  2-AG  induced by CBD regulates the production of antigens which increases the reproduction of new cells in replace of dead ones, hence fastening the internal healing process.
    • Working with vaped CBD, CB2 receptors induces relaxing effects in the brain neurons, which help you to fall asleep quickly and ensures you remain fresh, energetic, and alert during the day.

    CB1 Cannabinoid Receptors

    They are located in the nervous system, both peripheral and central. When you vape CBD, it quickly reaches the brain, increasing the production of anandamide that binds with CB1 receptors to tackle emotional problems and brain inflammations. Vaped CBD works with CB1 receptors to exhibit the following benefits:

    Increase the release of enzymes and kinase, which breaks down hormone cytokines. The hormone occurs when you are stressed or tensed; thus, you feel calm and relaxed when it's reduced.

    • Vaped CBD and CB2 receptors allow the brain cells to produce more stress-relieving hormone serotonin, which regulates mood by changing how the brain perceives negative thoughts.
    • Aid in memory formation to tackle memory loss caused by mental ailments like ADHD and PSTD. Vaped CBD activates the production of brain molecules called adenylyl cyclase, which helps in recovering memory loss and formation of new ones and further prevent the spread of mental disorders.
    • Reduced pain in most body parts since CBD is known to exhibit anti-inflammatory properties. CB1 bind with CBD-induced anandamide to reduce any signaling of pain terminals in the nervous system making you feel calm and less anxious.
    • The interaction of vape CBD, CB1, and anandamide boosts your body's movements. Some CB1 receptors are located in the brain's basal ganglia and bind with anandamide to help in the body's signals by inhibiting the release of GABA transmitters which influences the body to stay still and come. CBD affects the receptors in the peripheral nervous system to interact with peripheral terminals of the spinal cord to signal the muscles and bones in the legs to make a move.

    Conclusion

    CBD products have gained massive popularity in people's lifestyles as they discover how powerful they are in reducing body pains, anxiety, and stress, improving sleep quality, and treating chronic diseases like arthritis, acne, and even cancer. CBD vape oil is easy and convenient since it involves simply vaping and inhaling the vapor into your bloodstream. It interacts with ECS receptors to increase the release of body cannabinoids that binds with CB1 and CB2 receptors to help you tackle any imbalances you are experiencing.

    References

    Conuel, E. J., Chieng, H. C., Fantauzzi, J., Pokhrel, K., Goldman, C., Smith, T. C., ... & Judson, M. A. (2020). Cannabinoid Oil Vaping-Associated Lung Injury And Its Radiographic Appearance. The American Journal Of Medicine, 133(7), 865-867.

    Corroon, J., & Felice, J. F. (2019). The Endocannabinoid System And Its Modulation By Cannabidiol (CBD). Alternative Therapies In Health & Medicine, 25.

    He, T., Oks, M., Esposito, M., Steinberg, H., & Makaryus, M. (2017). "Tree-In-Bloom": Severe Acute Lung Injury Induced By Vaping Cannabis Oil. Annals Of The American Thoracic Society, 14(3), 468-470.

    Vaccani, A., Massi, P., Colombo, A., Rubino, T., & Parolaro, D. (2005). Cannabidiol Inhibits Human Glioma Cell Migration Through A Cannabinoid Receptor‐Independent Mechanism. British Journal Of Pharmacology, 144(8), 1032-1036.

    Nicola Boulton
    Nicola Boulton


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